Antibody-mediated blockade of phosphatidylserine enhances the anti-tumor activity of targeted therapy and immune checkpoint inhibitors by affecting myeloid and lymphocyte populations in the tumor microenvironment

Adam Yopp; Nikoletta Kallinteris; Xianming Huang; Joe Shan; Kerstin Menander; Bruce Freimark; Jeff Hutchins; Steve King; Dmitry I Gabrilovich; Rolf Brekken

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Antibody-mediated blockade of phosphatidylserine enhances the anti-tumor activity of targeted therapy and immune checkpoint inhibitors by affecting myeloid and lymphocyte populations in the tumor microenvironment

机译：抗体介导的磷脂酰丝氨酸阻断作用通过影响肿瘤微环境中的髓样和淋巴细胞群体，增强了靶向治疗和免疫检查点抑制剂的抗肿瘤活性

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来源
《Journal for ImmunoTherapy of Cancer》 |2014年第s3期|共页
作者
Adam Yopp; Nikoletta Kallinteris; Xianming Huang; Joe Shan; Kerstin Menander; Bruce Freimark; Jeff Hutchins; Steve King; Dmitry I Gabrilovich; Rolf Brekken;
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中图分类肿瘤学;
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3. Targeting of phosphatidylserine by monoclonal antibodies enhances activity of immune checkpoint inhibitors in breast tumors [J] . Jian Gong, Van Nguyen, Shen Yin, Journal for ImmunoTherapy of Cancer . 2014,第S3期

机译：单克隆抗体靶向磷脂酰丝氨酸可增强乳腺肿瘤中免疫检查点抑制剂的活性
4. Photodynamic therapy stimulates anti-tumor immune response in mouse models: the role of regulatory T-cells, anti-tumor antibodies, and immune attack on brain metastases [C] . Fatma Vatansever, Masayoshi Kawakubo, Hoon Chung, Biophotonics and immune responses VIII . 2013

机译：光动力疗法在小鼠模型中刺激抗肿瘤免疫反应：调节性T细胞，抗肿瘤抗体的作用以及对脑转移瘤的免疫攻击
5. IMMUNE RESPONSE TO ULTRAVIOLET-INDUCED TUMORS: TRANSPLANTATION IMMUNITY AND LYMPHOCYTE POPULATIONS EXHIBITING ANTI-TUMOR ACTIVITY (CYTOLYTIC T, CLONES, NATURAL KILLER CELLS). [D] . STREETER, PHILIP REEL. 1985

机译：对紫外线诱导的肿瘤的免疫反应：移植免疫和具有抗肿瘤活性的淋巴细胞（细胞分裂性T，克隆，天然杀伤细胞）。
6. Antibody-mediated blockade of phosphatidylserine enhances the anti-tumor activity of targeted therapy and immune checkpoint inhibitors by affecting myeloid and lymphocyte populations in the tumor microenvironment [O] . Adam Yopp, Nikoletta Kallinteris, Xianming Huang, 2014

机译：抗体介导的磷脂酰丝氨酸阻断作用通过影响肿瘤微环境中的髓样和淋巴细胞群体增强了靶向治疗和免疫检查点抑制剂的抗肿瘤活性
7. Antibody-mediated blockade of phosphatidylserine enhances the anti-tumor activity of targeted therapy and immune checkpoint inhibitors by affecting myeloid and lymphocyte populations in the tumor microenvironment [O] . 2014

机译：抗体介导的磷脂酰丝氨酸阻断作用通过影响肿瘤微环境中的髓样和淋巴细胞群体，增强了靶向治疗和免疫检查点抑制剂的抗肿瘤活性
8. Enhancing the Anti-Tumor Activity of Breast Cancer-Specific Cytotoxic T Lymphocytes [R] . Malek, T. 2001

机译：增强乳腺癌特异性细胞毒性T淋巴细胞的抗肿瘤活性

Antibody-mediated blockade of phosphatidylserine enhances the anti-tumor activity of targeted therapy and immune checkpoint inhibitors by affecting myeloid and lymphocyte populations in the tumor microenvironment

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