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Time Course of Left Ventricular Pressure-Volume Relationship under Various Extents of Aortic Occlusion

机译：主动脉闭塞程度下左心室压力-容积关系的时程

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The author has reported that a variable, e(t)=p(t)/v(t), is approximately unchanged in the areflexive heart of the dog over a wide range of end-diastolic volume of the left ventricle, where p(t) is systolic left intraventricular pressure, v(t) is systolic left intraventricular volume, and t is time from the beginning of systole in each cardiac cycle. e(t) is studied further under various extents of an aortic occlusion, without the change in left intraventricular end-diastolic volume, monitored on left intraventricular end-diastolic pressure of the areflexive heart of the dog. For actual computation, e(t)=p(t)/{(1-ρ)-1?vs-∫toi(t)dt}, where p(t) is measured by a straingauge electromanometer, ρ is residual volume ratio measured by a thermodilution method, vs is stroke volume as time-integral of ascending aortic flow velocity i(t) in a given cardiac cycle, and i(t) is measured by an electromagnetic flowmeter. End-diastolic volumes of the left ventricle are kept approximately constant by controlling venous return to the heart with a balloon-catheter in the inferior vena cava. The results show that e(t) is approximately unchanged by an ascending aortic occlusion, in spite of the conspicuous changes in p(t), i(t) and v(t) in each dog. Therefore, e(t) is considered to be a steady and characteristic variable of the pumping properties of the areflexive left ventricle.
机译：作者报告说，变量e（t）= p（t）/ v（t）在左心室舒张末期容积很大的范围内，在狗的自反性心脏中几乎没有变化，其中p（ t）是收缩期左心室压力，v（t）是收缩期左心室容积，t是从每个心动周期收缩开始的时间。 e（t）在主动脉闭塞的各种程度下进行了进一步研究，而没有改变左心室舒张末期左心室舒张末期容积，通过对狗的屈曲性心脏的左心室舒张末期压力进行监测。对于实际计算，e（t）= p（t）/ {（1-ρ）-1？vs-∫toi（t）dt}，其中p（t）是通过应变计压力计测量的，ρ是剩余体积比在一定的心动周期内，通过热稀释法测量的搏动量与作为升主动脉流速i（t）的时间积分的搏动量之间的关系;通过电磁流量计测量i（t）。左心室舒张末期容积通过下腔静脉中的球囊导管控制静脉回流至心脏而保持大致恒定。结果显示，尽管每只狗的p（t），i（t）和v（t）发生了明显变化，但主动脉闭塞e（t）几乎不变。因此，e（t）被认为是柔韧性左心室的泵送特性的稳定且特征性变量。

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