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Self-reported Sleep Duration and Subclinical Atherosclerosis in a General Population of Japanese Men

机译:日本男性普通人群的自我报告的睡眠时间和亚临床动脉粥样硬化

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Aim : There are few data regarding associations between sleep duration and subclinical atherosclerosis in Japan. The aim of this study was to evaluate associations of self-reported sleep duration with calcification in the coronary arteries (CAC) and carotid intima media thickness (IMT) in Japanese men. Methods : This was a cross-sectional survey of 1093 randomly selected men from Kusatsu City, Japan. Average sleep duration on weekdays was estimated through questionnaire; CAC by computed tomography; and carotid IMT by ultrasonography. Results : The prevalence of CAC was 50.0% for participants with sleep duration <5.5 h, 43.9% with 5.5–6.4 h, 50.0% with 6.5–7.4 h, 49.3% with 7.5–8.4 h, and 62.5% with ≥8.5 h. In univariate analysis, participants with sleep duration ≥8.5 h had significantly higher prevalence of CAC than those with 6.5–7.4 h ( p =0.043). After adjustment for age and other risk factors, however, the association was not significant ( p =0.776). The average IMT was 0.85 mm for participants with sleep duration <5.5 h, 0.83 mm with 5.5–6.4 h, 0.85 mm with 6.5–7.4 h, 0.88 mm with 7.5–8.4 h, and 0.90 mm with ≥8.5 h. None of the differences in IMT observed in crude or multivariable-adjusted analyses was significant (all p >0.1). Conclusion : Self-reported sleep duration was not associated with increased CAC or carotid IMT in a general population of Japanese men.
机译:目的:关于日本睡眠时间与亚临床动脉粥样硬化之间关系的数据很少。这项研究的目的是评估日本男性自我报告的睡眠时间与冠状动脉钙化(CAC)和颈动脉内膜中层厚度(IMT)的相关性。方法:这是对来自日本草津市的1093名随机选择的男性进行的横断面调查。通过问卷调查估计平日的平均睡眠时间;通过计算机断层扫描进行CAC;超声检查颈动脉IMT。结果:睡眠时间<5.5 h的参与者的CAC患病率为50.0%,5.5-6.4 h为43.9%,6.5-7.4 h为50.0%,7.5-8.4 h为49.3%,≥8.5h为62.5%。在单因素分析中,睡眠时间≥8.5h的参与者的CAC患病率明显高于6.5–7.4 h的参与者(p = 0.043)。但是,在调整了年龄和其他危险因素后,该关联性并不显着(p = 0.776)。睡眠时间<5.5 h的参与者的平均IMT为0.85 mm,5.5-6.4 h的参与者为0.83 mm,6.5-7.4 h的参与者为0.85 mm,7.5-8.4 h的参与者为0.88 mm,≥8.5h的参与者为0.90 mm。在粗略或多变量调整分析中观察到的IMT差异均无统计学意义(所有p> 0.1)。结论:在日本男性人群中,自我报告的睡眠时间与CAC或颈动脉IMT增加无关。

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