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首页> 外文期刊>Journal of Applied Life Sciences International >The Effect of Immunotherapy on Some Immunological Parameters of Airway Allergic Patients in Province of Babylon/Iraq
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The Effect of Immunotherapy on Some Immunological Parameters of Airway Allergic Patients in Province of Babylon/Iraq

机译：免疫疗法对巴比伦/伊拉克省气道过敏患者某些免疫学指标的影响

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Twenty-fife blood samples had been collected from patients who attend the center of the allergy and asthma in the province of Babylon, 25 samples from patient who have received subcutaneous immunotherapy, 10 samples from non-allergic persons as a control. These samples were categorized into three groups (before treatment group, after treatment group and control group), the level of immune parameters, which includes histamine, IL-10 and IL-12 have been measured by using ELISA technique. The level of histamine for the first group (before treatment) has reached 34.8292±6.47680 ng/ml as compared with the second group (after treatment) which was 9.3238±3.55296 ng/ml and control is 6.9844±3.05477 ng/ml, while the level of IL-10 for the first groupis14.9604±6.48170 pg/ml as compared with second group which was 43.0476±21.26668 pg/ml and control is 24.4969±10.21066 pg/ml, finally the level of IL-12 for the first group was 17.753±8.39343 pg/ml as compared with second group which was 39.1929±17.73975 pg/ml and control 26.7731±12.93092 pg/ml. The group of immunotherapy treated patients was divided into four subgroups, according to the period of immunotherapy treatment which were two months, six months, twelvemonths and more than twenty-four months, It had been found that there was a gradual decrease in the level of histamine with increasing the period of immunotherapy treatment that are 11.1811±5.33203 ng/ml, 9.8948±2.91382 ng/ml, 8.8024±2.57390 ng/ml and 8.1191±5.76472 ng/ml respectively, on the contrary, for IL-10 its level increased with increasing the period of immunotherapy treatment that were 13.9605±2.36278 pg/ml, 39.5547±16.60696 pg/ml, 56.8740±11.15175 pg/ml and 65.6659±2.80207 pg/ml respectively. The same thing for the level of IL-12 which increased with increasing the period of immunotherapy treatment that were 16.1298±4.70059 pg/ml, 30.5796±5.40110 pg/ml, 54.0523±5.63154 pg/ml and 56.4601±1.24127 respectively.
机译：从参加巴比伦省过敏和哮喘病治疗中心的患者中采集了20份血样，从接受皮下免疫疗法的患者中采集了25份血样，从非过敏者中获得了10份血样作为对照。将这些样品分为三组（治疗前，治疗后和对照组），通过ELISA技术测定了免疫参数的水平，包括组胺，IL-10和IL-12。第一组（治疗前）的组胺水平已达到34.8292±6.47680 ng / ml，而第二组（治疗后）的组胺水平为9.3238±3.55296 ng / ml，对照组为6.9844±3.05477 ng / ml，而第一组的IL-10水平为14.9604±6.48170 pg / ml，第二组的IL-10水平为43.0476±21.26668 pg / ml，对照组为24.4969±10.21066 pg / ml，最后第一组的IL-12水平与第二组的39.1929±17.73975 pg / ml和对照组的26.7731±12.93092 pg / ml相比，其为17.753±8.39343 pg / ml。免疫治疗的患者按免疫治疗的时间段分为两个亚组，分别为两个月，六个月，十二个月和二十四个月以上，发现其水平逐渐降低。组胺随免疫治疗时间的延长分别为11.1811±5.33203 ng / ml，9.8948±​​2.91382 ng / ml，8.8024±2.57390 ng / ml和8.1191±5.76472 ng / ml，而IL-10的水平升高随着免疫治疗时间的延长，分别为13.9605±2.36278 pg / ml，39.5547±16.60696 pg / ml，56.8740±11.15175 pg / ml和65.6659±2.80207 pg / ml。随着免疫疗法治疗时间的增加，IL-12水平相同，分别为16.1298±4.70059 pg / ml，30.5796±5.40110 pg / ml，54.0523±5.63154 pg / ml和56.4601±1.24127。

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