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首页> 外文期刊>Journal of Armed Forces Medical College, Bangladesh >Effectiveness of Immunochromatographic Test in the Diagnosis of Falciparum Malaria
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Effectiveness of Immunochromatographic Test in the Diagnosis of Falciparum Malaria

机译：免疫层析法在恶性疟疾诊断中的有效性

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Introduction : Various diagnostic tools are used to confirm diagnosis of different types of malaria. Immunochromatographic test for Plasmodium falciparum (ICT malaria Pf) is one of them. Objective: Aim of this prospective study was to find out a rapid, effective and easy tool for the diagnosis of malaria for the hilly area of Bangladesh. Method: A prospective study was conducted at hilly area of Bangladesh over a period of 7 months. Clinically suspected 50 cases of malaria of both sexes of different age group were included in the study. Blood samples were collected and simultaneously microscopic examination of Leishman's stain film and ICT malaria Pf were done. Results were compared using standard method. Result: The mean age of the patients was 29.9±18 years and 49 were male. Among the 19 parasitaemic cases, 16 (84.2%) cases were Plasmodium falciparum positive, 02 (10.5%) cases were Plasmodium vivax positive and 01 (5.3%) was mixed infection. The degree of parasitaemia (malarial parasite count /cmm) ranges form 2000/cmm to 30,000/cmm with the mean 10,395±8,444/cmm. Among the 19 microscopically positive cases, 16 (84.2%) cases were ICT positive and 03 (15.8%) cases were ICT negative. The sensitivity of ICT for Pf in this study was 94.1% and the specificity of ICT for Pf was 100%. The positive predictive value (PPV) and negative predictive value (NPV) were 100% and 97.1% respectively Conclusion: The study revealed that the "ICT Malaria Pf has a very important role in the diagnosis of Plasmodium malaria. The sensitivity and specificity are approx 100% and very rapid in action.
机译：简介：各种诊断工具可用于确认对不同类型疟疾的诊断。恶性疟原虫（ICT疟疾Pf）的免疫层析测试就是其中之一。目的：这项前瞻性研究的目的是找到一种快速，有效和简便的工具来诊断孟加拉国丘陵地区的疟疾。方法：在孟加拉国的丘陵地区进行了为期7个月的前瞻性研究。该研究包括临床怀疑的50例不同年龄段性别的疟疾。收集血液样本，同时进行利什曼氏染色膜和ICT疟疾Pf的显微镜检查。使用标准方法比较结果。结果：患者的平均年龄为29.9±18岁，男性49例。在19例寄生虫病病例中，恶性疟原虫阳性16例（84.2％），间日疟原虫阳性02例（10.5％），混合感染01例（5.3％）。寄生虫血症的程度（疟原虫计数/ cmm）范围从2000 / cmm到30,000 / cmm，平均为10,395±8,444 / cmm。在19例镜检阳性病例中，ICT阳性16例（84.2％），ICT阴性03例（15.8％）。这项研究中ICT对Pf的敏感性为94.1％，而ICT对Pf的特异性为100％。结论：研究表明：“ ICT疟疾Pf在疟原虫疟疾的诊断中具有非常重要的作用。敏感性和特异性大约为100％，而NPV则为97.1％。 100％且动作迅速。

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