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首页> 外文期刊>Journal of Applied Life Sciences International >Antimicrobial Activity of Crude Methanol Extract of Fecal Droppings of Common House Lizard/Gecko (Hemidactylus frenatus)
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Antimicrobial Activity of Crude Methanol Extract of Fecal Droppings of Common House Lizard/Gecko (Hemidactylus frenatus)

机译：普通蜥蜴/壁虎粪便粪便粗甲醇提取物的抑菌活性

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Aims: This study was carried out to evaluate the antimicrobial activity of methanol extract of fecal droppings of common house lizard/gecko ( Hemidactylus frenatus ). Methodology: The antimicrobial activity of the methanol extract of fecal droppings of common house lizard/gecko was evaluated against the test organisms using the agar well diffusion method. Strains of Staphylococcus aureus, Escherichia coli, Salmonella typhi, Bacillus subtilis, Candida albicans and Aspergillus fumigates were used in this study. Result: At the concentrations analyzed (20-1.25 mg/mL), the extract recorded only antibacterial and no antifungal activity against the test isolates. Antibacterial activity was observed against all test bacteria except S. typhi . At 20 mg/mL inhibition zone diameters (IZDs) of 4, 0, 3 and 5mm were recorded against S. aureus, S. typhi, B. subtilis and E. coli respectively. At 5 mg/mL, antibacterial activity was recorded only against E. coli with an IZD of 2mm. Conclusion: This report reveals the potential of the fecal droppings of common house lizard/gecko for use as a source of antimicrobial agent.The potency of the crude extract could improve if the active ingredient is isolated and purified.
机译：目的：本研究旨在评价普通蜥蜴/壁虎粪便粪便甲醇提取物的抗菌活性。方法：使用琼脂井扩散法评估普通家蜥蜴/壁虎粪便粪便甲醇提取物的抗微生物活性。本研究使用金黄色葡萄球菌，大肠杆菌，伤寒沙门氏菌，枯草芽孢杆菌，白色念珠菌和熏蒸曲霉菌株。结果：在分析的浓度（20-1.25 mg / mL）下，提取物仅对测试分离株具有抗菌作用，而没有抗真菌活性。观察到对除伤寒沙门氏菌以外的所有测试细菌的抗菌活性。在20 mg / mL的浓度下，分别记录了针对金黄色葡萄球菌，伤寒沙门氏菌，枯草芽孢杆菌和大肠杆菌的4、0、3和5mm的抑制区直径（IZD）。在5 mg / mL时，仅记录到IZD为2mm的大肠杆菌的抗菌活性。结论：本报告揭示了普通家蜥蜴/壁虎粪便粪便作为抗菌剂来源的潜力。如果将活性成分分离和纯化，则粗提物的效力会提高。

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