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首页> 外文期刊>Journal of atherosclerosis and thrombosis. >Associations between Socioeconomic Status and the Prevalence and Treatment of Hypercholesterolemia in a General Japanese Population: NIPPON DATA2010
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Associations between Socioeconomic Status and the Prevalence and Treatment of Hypercholesterolemia in a General Japanese Population: NIPPON DATA2010

机译：日本普通人群的社会经济地位与高胆固醇血症的发生和治疗之间的关联：NIPPON DATA2010

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Aim : To investigate associations between socioeconomic status (SES) and the prevalence and treatment status of hypercholesterolemia in a general Japanese population. Methods : In 2010, we established a cohort study of 2417 adults (age 20–91 yr) from 300 randomly selected areas across Japan who participated in the National Health and Nutrition Survey of Japan. We cross-sectionally examined an association between SES and (1) prevalence of hypercholesterolemia in 2417 participants (999 men and 1418 women) and (2) not receiving medication for hypercholesterolemia in 654 participants (215 men and 439 women). SES included employment status, marital status, length of education, and household expenditures. Hypercholesterolemia was defined as a total serum cholesterol level of ≥6.21 mmol/L (240 mg/dL) or the use of lipid-lowering medications. Results : The overall prevalence of hypercholesterolemia was 21.5% in men and 31.0% in women. In men, the lowest quintile of household expenditures was associated with a higher prevalence of hypercholesterolemia (28.3%) compared with the upper 4 quintiles (19.9%) (multivariable-adjusted odds ratio 1.66; 95% confidence interval [CI] 1.16–2.38). Among participants with hypercholesterolemia, 55.4% of men and 55.1% of women were not receiving medication. Unmarried men were more likely to be untreated (75.0%) than married men (50.9%) (multivariable-adjusted odds ratio 2.53;95%CI 1.05–6.08). SES had no significant effects in women. Conclusion : In a general population of Japanese men, low household expenditures were associated with a higher prevalence of hypercholesterolemia, and unmarried men with hypercholesterolemia were less likely to receive medication.
机译：目的：调查一般日本人群的社会经济状况（SES）与高胆固醇血症的患病率和治疗状况之间的关联。方法：2010年，我们对来自日本300个随机选择的地区的2417名成年人（年龄在20-91岁之间）进行了队列研究，他们参加了日本国家健康与营养调查。我们横断面检查了SES与（1）2417名受试者（999名男性和1418名女性）的高胆固醇血症患病率和（2）654名受试者（215名男性和439名女性）未接受高胆固醇血症药物治疗之间的相关性。 SES包括就业状况，婚姻状况，受教育时间和家庭支出。高胆固醇血症定义为血清总胆固醇≥6.21 mmol / L（240 mg / dL）或使用降脂药。结果：男性高胆固醇血症的总体患病率为21.5％，女性为31.0％。在男性中，家庭支出的最低五分位数与高胆固醇血症的患病率（28.3％）相比，高四分之五（19.9％）的患病率高（多变量校正比值比为1.66; 95％的置信区间[CI] 1.16–2.38） 。在患有高胆固醇血症的参与者中，有55.4％的男性和55.1％的女性未接受药物治疗。未婚男子比未婚男子（50.9％）更容易受到未治疗（75.0％）（多变量调整后的优势比为2.53; 95％CI 1.05-6.08）。 SES对女性没有明显影响。结论：在日本男性人群中，家庭支出低与高胆固醇血症的患病率较高相关，未婚高胆固醇血症的男性接受药物治疗的可能性较小。

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