...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Behavioral and Brain Science >Executive Functions Assessment in Adult Patients with Idiopathic Epilepsy
【24h】

Executive Functions Assessment in Adult Patients with Idiopathic Epilepsy

机译：成年特发性癫痫患者的执行功能评估

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective: Cognitive impairments are common complaints among people with epilepsy with its occurrence to emanate a great topic in the course of the illness, so our study aimed to examine the executive functions in adult patients with idiopathic epilepsy. Methods: Forty consecutive adult patients with idiopathic epilepsy (either generalized or focal) with age range from 18 - 45 years old, IQ > 85, treated with either monotherapy or polytherapy, matched with forty healthy adult volunteers by age, sex and educational level. They were examined in executive functions tests: cognitive flexibility and set shifting (Wisconsin Card sorting Test), Planning (Tower of London), response inhibition (Continuous Performance Test) and working memory (verbal and visuospatial). Results: Patients with epilepsy showed deficits in all executive functions tests, with no difference between patients with generalized and focal epilepsy except for correct response time mean in CPT. There was significant positive correlation between frequency of seizures and mean total time, mean number of extra movies in TOL, in verbal working memory (digit back word), and omission errors in CPT; at the same time there was significant negative correlation between target accuracy rate and frequency of seizures in CPT, and in visuo-spatial part of working memory (Corsi Block-Tapping Test). Conclusion: Adult patients with idiopathic epilepsy had executive dysfunctions than healthy control, with no difference between generalized and focal epilepsy except for correct response time mean in CPT; the increase of the frequency of seizure is associated with impairment in planning, attention and working memory (either verbal or viuso-spatial).
机译：目的：认知障碍是癫痫患者中常见的主诉，其发生在疾病过程中是一个重要话题，因此我们的研究旨在检查成年特发性癫痫患者的执行功能。方法：连续40例年龄在18-45岁，智商> 85的特发性癫痫（全身性或局灶性）成人患者，接受单一疗法或综合疗法治疗，按年龄，性别和教育水平与40名健康成人志愿者相匹配。在执行功能测试中对它们进行了检查：认知灵活性和集合转移（威斯康星卡片分类测试），计划（伦敦塔），反应抑制（连续表现测试）和工作记忆（语言和视觉空间）。结果：癫痫患者在所有执行功能测试中均显示出缺陷，除了CPT的正确反应时间均值外，全身性和局灶性癫痫患者之间没有差异。癫痫发作频率与平均总时间，TOL中额外的平均电影数量，口头工作记忆（指背单词）和CPT中的遗漏错误之间存在显着正相关。同时，在CPT中以及在工作记忆的视觉空间部分中，目标准确率与癫痫发作频率之间存在显着的负相关性（Corsi敲击测试）。结论：成年特发性癫痫患者的执行功能较健康对照者差，一般性和局灶性癫痫患者之间无差异，但CPT的平均反应时间均正确。癫痫发作频率的增加与计划，注意力和工作记忆（言语或视觉空间）的损害有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号