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首页> 外文期刊>Journal of Biosciences and Medicines >Study on the Corneal Higher-Order Aberrations and Correlation in Patients with Different Degrees of Myopia Suitable for Wavefront-Guided FS-LASIK
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Study on the Corneal Higher-Order Aberrations and Correlation in Patients with Different Degrees of Myopia Suitable for Wavefront-Guided FS-LASIK

机译：适用于波前引导FS-LASIK的近视度数不同的患者的角膜高阶像差及相关性研究

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Background: Individualized corneal refractive surgery requires an understanding of the basis of higher-order aberrations before surgery. To investigate the characteristics and distribution of anterior surface wavefront aberrations in patients suitable for corneal refractive surgery. Methods: A total of 121 myopic patients (121 eyes, 18 - 45 years old) who underwent corneal refractive surgery were recruited from January to May 2016 at Affiliated Hospital, Yanbian University. Patients were randomly selected by the Pentacam anterior segment analysis system with a spherical equivalent (SE) of -0.25 to -10.00 D. The corneal anterior aberrations (total higher-order aberration; spherical aberration; Coma; Trefoil) and Q and K values were detected, and a correlation analysis of the relevant parameters was carried out. Results: The root-mean-square (RMS) of the third to sixth order aberrations of the corneal anterior wavefront aberrations at a 6 mm analysis diameter showed a decreasing trend in patients suitable for the corneal refractive surgery, and the RMS of the third order aberrations accounted for 62.92% of the total HOAs. The coma ratio (coma/total cornea higher-order aberrations) was increased with the increasing diopters, while the spherical aberration ratio (spherical aberration/total cornea higher-order aberrations) was not changed. In addition, the spherical aberration was 0.203 ± 0.082 μm (range: 0.061 to 0.503 μm), and the Q_(30) was -0.19 ± 0.03 (range: -0.58 to 0.31). There were significant differences in the coma aberrations of preoperative corneal anterior surface (3, 1) between the low, middle and high myopia groups (P = 0.013). The spherical equivalent was positively correlated with the corneal coma of the anterior corneal surfaces (R =?- 0.241, P = 0.009), and the Q value was positively correlated with the total higher-order aberrations (R = 0.326, P < 0.001). Conclusions: Individual wavefront aberrations on the anterior surfaces of the cornea are comparatively different, and the Zernike coefficients are related to the degree of myopia. Spherical aberrations are the most overriding aberrations of the cornea.
机译：背景：个性化角膜屈光手术需要在手术前了解高阶像差的基础。目的探讨适合角膜屈光手术的患者前表面波阵面像差的特征和分布。 方法：2016年1月至2016年1月至2016年1月至5月，在延边大学附属医院招募了共121例近视患者（121眼，年龄18-45岁）。通过Pentacam前段分析系统随机选择患者，其球当量（SE）为-0.25至-10.00D。角膜前像差（总高阶像差;球面像差;彗差;三叶形）以及Q和K值为检测，并进行相关参数的相关分析。 结果：在适用于角膜屈光手术的患者中，直径为6 mm的角膜前波前像差的三阶至六阶像差的均方根（RMS）显示出下降的趋势，并且第三阶像差占HOA总数的62.92％。彗差比（彗差/总角膜高阶像差）随屈光度的增加而增加，而球差比（球面像差/角膜总高阶像差）不增加改变了。另外，球差为0.203±0.082μm（范围：0.061至0.503μm），并且Q_（30）为-0.19±0.03（范围：-0.58至0.31）。在低，中，高度近视组之间，术前角膜前表面（3、1）的彗形像差存在显着差异（P = 0.013）。球形当量与角膜前表面的角膜昏迷呈正相关（ R = -0.241 ，P = 0.009），而Q值与总体前角呈正相关阶像差（R = 0.326，P <0.001）。 结论：角膜前表面的波前像差相对不同，Zernike系数与近视程度有关。球差是角膜最重要的像差。

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