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首页> 外文期刊>Journal of Biology, Agriculture and Healthcare >Long-term effect of iodized water and iodized oil supplementation on total goitre rate and nutritional status of school children in Ngargoyoso sub-district, Karanganyar regency, Central Java, Indonesia
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Long-term effect of iodized water and iodized oil supplementation on total goitre rate and nutritional status of school children in Ngargoyoso sub-district, Karanganyar regency, Central Java, Indonesia

机译：印度尼西亚中爪哇省Karanganyar地区Ngargoyoso分区加碘水和加碘油对小学生总甲状腺肿率和营养状况的长期影响

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Background: Ngargoyoso sub-district, Karanganyar regency, Central Java province, Indonesia, can be classified as severe IDD endemic area with TGR 51.9%. People get drinking water from spring-wells which contain no iodine. Drinking water has been distributed via pipelines directly to people’s home. Objectives: The ultimate goal of the study was to supplement people’s drinking water with iodine. The present study was designed to test hypothesis that iodine supplementation into drinking water was effective as iodized oil delivered in capsules. Methods: Eight hundred school children from year two and year four in Ngargoyoso sub-district were randomly assigned into two groups. The first group (N=407) received 100 mg iodine capsules (Yodiol?, Kimia Farma, Indonesia) and the second group (N=393) received 100 μg KIO3 daily via drinking water. Urinary iodine excretion (UIE) was measured using Method A (ammonium persulfate) in an accredited IDD Laboratory in Magelang, Central Java, Indonesia. Goitre prevalence was measured by palpation method. Total goitre rate (TGR) is the sum of grade 1 and grade 2. Nutritional status was measured as z-score of weight for age, height for age and weight for height using WHO Anthro (2005). Statistical analysis was performed using SPSS for Windows release 17.0 (Chicago, IL, USA). Results: Urinary iodine excretion increased in both groups. In the capsule group there was an increase of UIE from 244.16 (±104.37) μg/L to 522.91(±315.83) μg/L (p0.05). Nutritional status was not affected by iodine supplementation in both groups. Conclusion: Iodine supplementation into drinking water was effective as iodized oil in capsule in reducing goitre prevalence among school children in Ngargoyoso sub-district, Karanganyar regency, Central Java Province, Indonesia.
机译：背景：印度尼西亚中爪哇省卡兰甘雅尔区的Ngargoyoso街道可归类为严重IDD流行地区，TGR为51.9％。人们从不含碘的泉水井中获得饮用水。饮用水已通过管道直接分配到人们的家中。目的：这项研究的最终目标是用碘补充人们的饮用水。本研究旨在测试以下假设：将碘补充到胶囊中作为碘油注入饮用水是有效的。方法：将Ngargoyoso街道的第二年和第四年的800名学童随机分为两组。第一组（N = 407）每天接受100毫克碘胶囊（Yodiol？，Kimia Farma，印度尼西亚），第二组（N = 393）每天通过饮用水接受100微克KIO3。在印度尼西亚中爪哇省马格朗的IDD认可实验室中，使用方法A（过硫酸铵）测量了尿碘排泄量（UIE）。通过触诊法测量甲状腺肿患病率。总甲状腺肿率（TGR）是1级和2级的总和。使用WHO Anthro（2005）将营养状况测量为体重的z分数，年龄的身高和体重的z分数。使用SPSS for Windows版本17.0（芝加哥，伊利诺伊州，美国）进行统计分析。结果：两组的尿碘排泄均增加。胶囊组的UIE从244.16（±104.37）μg/ L增加到522.91（±315.83）μg/ L（p0.05）。两组的营养状况均不受补充碘的影响。结论：在印度尼西亚中爪哇省卡兰甘雅摄政区恩加格约索地区，饮用水中补充碘作为胶囊中的碘油可有效降低学童甲状腺肿患病率。

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