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首页> 外文期刊>Journal of Advances in Biomedical Studies >Co-infection of Sexually Transmitted Infections in Adult Male Patients with Urethral Discharge: A need to strengthen surveillance in HIV -1 infected patients.
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Co-infection of Sexually Transmitted Infections in Adult Male Patients with Urethral Discharge: A need to strengthen surveillance in HIV -1 infected patients.

机译：成年男性尿道分泌物性传播感染的共同感染：需要加强对HIV -1感染患者的监测。

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The study aimed to evaluate sexually transmitted pathogens in a high risk sample population of men with urethritis. Urethral were collected from 400 men with urethritis and processed for common sexually transmitted pathogens such as?Neisseria gonorrhoeae?and?Chlamydia trachomatis. Plate culture, microscopy and tissue cultures, were used to detect the presence of?Neisseria?gonorrhoeae,?Chlamydia trachomatis and?Herpes simplex virus?(HSV).?Screen for syphilis (Rapid Plasma Reagin-Becton Dickinson) and Human immunodeficiency virus?(HIV) (Determine, Abbott, USA) were performed according to manufacturer’s instructions.?Neisseria gonorrhoea?(84%; OR 2.0, 95% Cl: 1.0-3.0) was the major causative organism followed by?Chlamydia trachomatis?(65.5%; OR 1.9; 95% Cl: 1.3- 2.8).? Serological results for syphilis on HIV positive patients reflected 17.5 % with antibodies. There was a significant association with?N gonorrhoeae/C trachomatis?and the number of sexual partners encountered (p = 0.03). In conclusion, the sample population revealed high rates of sexually transmitted infections.? There were significant associations between STIs and continued high risk sexual practices in men. Sexually transmitted infections (STI) encourage risk factors for HIV infection, when it breaches’ the protective mucosal barriers and invade the immune system.? Therefore, these findings support the need for studies that confirm the percentage of STIs using both “point of care” methodologies and clinical laboratory tests.
机译：该研究旨在评估尿道炎男性高危人群中的性传播病原体。从400名患有尿道炎的男性中收集尿道，并处理常见的性传播病原体，例如“淋病奈瑟氏球菌”和“沙眼衣原体”。平板培养，显微镜检查和组织培养用于检测“奈瑟氏球菌”，“沙眼衣原体”和“单纯疱疹病毒”（HSV）的存在。 （HIV）（Determine，Abbott，USA）按照制造商的说明进行。淋病奈瑟菌（84％; OR 2.0，95％Cl：1.0-3.0）是主要的致病菌，其次是沙眼衣原体（65.5％）。 ;或1.9; 95％Cl：1.3- 2.8）。 HIV阳性患者的梅毒血清学结果显示，抗体的阳性率为17.5％。与“淋病奈瑟氏球菌/沙眼衣原体C”和所遇到的性伴侣的数量之间存在显着关联（p = 0.03）。总之，样本人群显示出较高的性传播感染率。性传播感染与男性持续的高风险性行为之间存在显着关联。性传播感染（STI）破坏了保护性粘膜屏障并侵袭了免疫系统，因此助长了HIV感染的危险因素。因此，这些发现支持需要使用“护理点”方法和临床实验室测试来确认性传播感染百分比的研究。

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