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首页> 外文期刊>Journal of Cachexia, Sarcopenia and Muscle >Sarcopenia and physical independence in older adults: the independent and synergic role of muscle mass and muscle function
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Sarcopenia and physical independence in older adults: the independent and synergic role of muscle mass and muscle function

机译：老年人的少肌症和身体独立性：肌肉质量和肌肉功能的独立和协同作用

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Abstract Background The loss of skeletal muscle mass (MM) or muscle function (MF) alone increases the risk for losing physical independence in older adults. We aimed to examine the independent and synergic associations of low MM and low MF, both criteria of sarcopenia, with the risk for losing projected physical independence in later life (+90 years old). Methods Cross-sectional analyses were conducted in 3493 non-institutionalized older adults (1166 males). Physical independence was assessed with a 12-item composite physical function scale. Logistic regression was used to estimate the odds-ratio (OR) for being at risk for losing physical independence. Results Approximately 30% of the participants were at risk for losing physical independence at 90 years of age. Independent analysis demonstrated that participants with low MM had 1.65 (95%CI: 1.27?￠????2.31) increased odds for being at risk for losing physical independence and participants with low MF had 6.19 (95%CI 5.08?￠????7.53) increased odds for being at risk. Jointly, having a low MM and a low MF increased the risk for losing physical independence to 12.28 (95%CI 7.95 to 18.96). Conclusions Although low MM represents a risk factor for losing physical independence, low MF seems to play a more dominant role in this relationship, with the presence of both sarcopenia criteria representing a substantial risk for losing physical independence in later life.
机译：摘要背景单独丧失骨骼肌质量（MM）或肌肉功能（MF）会增加老年人失去身体独立性的风险。我们的目的是检查低肌肉勃起症和低肌肉勃起症的独立和协同关系，这两个都是肌肉减少症的标准，在以后的生活中（+90岁）可能会失去预期的身体独立性。方法对3493例非住院的老年人（1166例男性）进行横断面分析。身体独立性用12个项目的综合身体功能量表进行评估。使用Logistic回归估计可能丧失身体独立性的风险的比值比（OR）。结果大约30％的参与者在90岁时有丧失身体独立性的风险。独立分析表明，MM低的参与者面临失去身体独立风险的几率增加1.65（95％CI：1.27？2.31）2.31，MF低的参与者具有6.19（95％CI 5.08）。 7.53）处于危险中的可能性增加。较低的MM和较低的MF共同使失去身体独立性的风险增加到12.28（95％CI从7.95到18.96）。结论尽管低MM是失去身体独立性的危险因素，但低MF在这种关系中似乎起着更主要的作用，同时存在两种肌肉减少症标准也代表着在以后的生活中丧失身体独立性的巨大风险。

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