Current and emerging breast cancer biomarkers

Maryam Sana; Hassan Jameel Malik

首页> 外文期刊>Journal of Cancer Research and Therapeutics >Current and emerging breast cancer biomarkers

【24h】

Current and emerging breast cancer biomarkers

机译：当前和新兴的乳腺癌生物标志物

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Breast cancer treatment has experienced several advancements in the past few decades with the discovery of specific predictive and prognostic biomarkers that make possible the application of individualized therapies. In addition to traditional prognostic factors of breast carcinoma, molecular biomarkers have played a significant role in tumor prediction and treatment. The most frequent genetic alterations of breast cancer are gained along chromosome 1q, 8q, 17q, 20q, and 11q and losses along 8p, 13q, 16q, 18q, and 11q. Interestingly, many of these chromosomal fragments harbor known proto oncogenes or tumor suppressor genes such as BRCA1, BRCA2, p53, HER2-neu, cyclin D1, and cyclin E, which are briefly described in this review.

机译：在过去的几十年中，随着特定的预测性和预后性生物标志物的发现，乳腺癌的治疗取得了几项进展，这使个体化疗法的应用成为可能。除了传统的乳腺癌预后因素外，分子生物标志物在肿瘤的预测和治疗中也起着重要的作用。乳腺癌最常见的遗传改变是从1q，8q，17q，20q和11q染色体获得的，而在8p，13q，16q，18q和11q的丢失则是遗传的。有趣的是，这些染色体片段中的许多片段都包含已知的原癌基因或抑癌基因，例如BRCA1，BRCA2，p53，HER2-neu，cyclin D1和cyclin E，在本综述中对此进行了简要介绍。

著录项

来源
《Journal of Cancer Research and Therapeutics》 |2015年第3期|共6页
作者
Maryam Sana; Hassan Jameel Malik;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词

相似文献

外文文献
中文文献
专利

1. Prediction of Late Recurrence and Distant Metastasis in Early-stage Breast Cancer: Overview of Current and Emerging Biomarkers [J] . Gouri A., Benarba B., Dekaken A., Current drug targets-The International journal for timely in-depth reviews on drug targets . 2020,第10期

机译：早期乳腺癌晚期复发和远端转移的预测：当前和新兴生物标志物概述
2. Current and emerging biomarkers in breast cancer: prognosis and prediction [J] . Marion T Weigel^1, Mitch Dowsett^12 Endocrine-related cancer . 2010,第4期

机译：乳腺癌的当前和新兴生物标志物：预后和预测
3. Is the TNM Staging System for Breast Cancer Still Relevant in the Era of Biomarkers and Emerging Personalized Medicine for Breast Cancer - An Institution's 10-year Experience [J] . Orucevic Amila, Chen Jason, McLoughlin James M., The breast journal . 2015,第2期

机译：TNM乳腺癌分期系统在生物标志物时代和新兴的乳腺癌个性化医学时代是否仍然有意义-机构的10年经验
4. Correlation Between Glycan Biomarkers of Human Breast Cancer and a Mouse Model of Metastatic Breast Cancer [C] . Maria Lorna A. de Leoz, Lawrence J. T. Young, Hyun Joo An, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：人乳腺癌甘油生物标志物与转移性乳腺癌小鼠模型的相关性
5. Identifying biomarkers for resistance to novel cisplatin analogues in human breast, lung and prostate cancers. [D] . Hess, Becky Michelle. 2009

机译：鉴定对人乳腺癌，肺癌和前列腺癌中新的顺铂类似物具有抗性的生物标志物。
6. Personalized Medicine—Current and Emerging Predictive and Prognostic Biomarkers in Colorectal Cancer [O] . Christine Koulis, Raymond Yap, Rebekah Engel, 2020

机译：个性化医学—结直肠癌中当前和新兴的预测和预后生物标志物
7. Current and emerging breast cancer biomarkers [O] . Maryam Sana, Hassan Jameel Malik 2015

机译：目前和新兴的乳腺癌生物标志物
8. Identification of Breast Cancer Serum Biomarkers: A Novel Retroviral Library Screen to Define the Breast Cancer-Soluble Ectodomain Proteome [R] . Paulovich, A., Lin, B. Y., Garton, K. J. 2009

机译：鉴定乳腺癌血清生物标志物：一种新的逆转录病毒库筛选，以确定乳腺癌可溶性胞外域蛋白质组

Current and emerging breast cancer biomarkers

摘要

著录项

相似文献

相关主题

期刊订阅