...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Cardiovascular Disease Research >Castelli Index and estimative of LDL-c particle size may still help in the clinical practice?
【24h】

Castelli Index and estimative of LDL-c particle size may still help in the clinical practice?

机译：Castelli指数和LDL-c粒径的估计仍可在临床实践中有所帮助吗？

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: There are many factors affecting the maintenance of a healthy in the population without coronary artery disease as plasmatic lipids and anthropometric parameters. This study aimed to evaluate the correlation between the Castelli Index I, Castelli Index II and the estimated size of the LDL-c particle with the presence of Coronary Artery Disease risk factors in patients undergoing coronary angiography. Methods: Anthropometric (waist circumference and body mass index) and biochemical parameters (glycaemia, total cholesterol, triglycerides, LDL-c, HDL-c and high sensitivity C-reactive protein) from 95 patients undergoing coronary arteriography were collected. Castelli Index I (TC/HDL-c), Castelli Index II (LDL-c/HDL-c) and the estimate of LDL particle size (TG/HDL-c) were calculated. Results: Our findings show that, in general, for abnormal values of the three rations cited above, there was a positive correlation with increased levels of serum lipids and that there are high percentages of subjects with increased values of WC, BMI and hsCRP and also the presence of MS, physical inactivity and family story of heart disease. Most patients with severe lesions in the arteries presented altered Castelli Index II and small dense LDL-c particle. Conclusion: The use of these tree ratios may represent simple parameters for estimating cardiovascular risks patients with heart disease diagnosis in order to work on secondary prevention.
机译：背景：血浆脂质和人体测量学参数有很多因素会影响没有冠心病的人群的健康维持。这项研究旨在评估在进行冠状动脉造影的患者中，Castelli指数I，Castelli指数II与LDL-c颗粒的估计大小之间的相关性，其中存在冠心病危险因素。方法：收集95例接受冠状动脉造影的患者的人体测量学（腰围和体重指数）和生化参数（血糖，总胆固醇，甘油三酸酯，LDL-c，HDL-c和高敏感性C反应蛋白）。计算了卡斯特利指数I（TC / HDL-c），卡斯特利指数II（LDL-c / HDL-c）和LDL粒径的估算值（TG / HDL-c）。结果：我们的发现表明，通常，对于上述三种口粮的异常值，与血脂水平升高呈正相关，并且有较高百分比的受试者的WC，BMI和hsCRP值升高，并且MS的存在，缺乏运动和心脏病的家庭故事。大多数动脉严重病变的患者表现出Castelli Index II改变和小的致密LDL-c颗粒。结论：使用这些树比率可以代表简单的参数来估计心脏病诊断的心血管风险，以便进行二级预防。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号