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The Epidemiological Scale of Alzheimer’s Disease

机译：阿尔茨海默氏病的流行病学规模

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Alzheimer’s disease (AD) has increased from a few cases in a country at the beginning of the 20th century to an incidence of recording a case every 7 seconds in the world. From a rare disease it has reached the top 8 of major health problems in the world. One of the epidemiological problems of AD is the fact that authors from different countries use different reporting units. Some report numbers to 100,000 inhabitants, others to 1,000 inhabitants and others report the total number of cases in a country. Standardization of these reports is strictly necessary. The rise in incidence and prevalence with age is known, but interesting to see is that the incidence and prevalence do not rise in a parallel manner with age as simple logic would assume. Between the ages of 60 and 90, the incidence in men increases two times and in women 41 times, prevalence increase in men is 55.25-fold and in women 77-fold. Regarding the women/men ratio, the incidence is 20.5-fold increased, and prevalence is merely 1.3936-fold increased. These numbers raise concerns about the evolution of the disease. Regarding mild cognitive impairment (MCI)/AD ratio, only about 1 in 2 people get AD (raising?) issues about the pathogenic disease relatedness.J Clin Med Res. 2015;7(9):657-666doi: http://dx.doi.org/10.14740/jocmr2106w
机译：阿尔茨海默氏病（AD）的发病率从20世纪初的一个国家的几例上升到了全世界每7秒记录一次的病例。从一种罕见的疾病到世界上主要的健康问题，它已经达到了前八位。 AD的流行病学问题之一是来自不同国家的作者使用不同报告单位的事实。一些报告了100,000居民的人数，另一些报告了1,000居民的人数，其他报告了一个国家的病例总数。这些报告的标准化是绝对必要的。发病率和患病率随年龄的增长是已知的，但有趣的是，发病率和患病率并不会像简单的逻辑假设那样随年龄的增长而平行上升。在60至90岁之间，男性的发病率增加了两倍，女性的发病率增加了41倍，男性的患病率增加了55.25倍，女性则增加了77倍。关于男女比例，发病率增加了20.5倍，患病率仅增加了1.3936倍。这些数字引起了人们对这种疾病演变的担忧。关于轻度认知障碍（MCI）/ AD比率，只有大约每2人中有1人会得到与病原体疾病相关性的AD（升高？）问题。JClin Med Res。 2015; 7（9）：657-666doi：http://dx.doi.org/10.14740/jocmr2106w

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