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首页> 外文期刊>Journal of Clinical Medicine Research >Antibiotics for Post-Tonsillectomy Morbidity: Comparative Analysis of a Single Institutional Experience
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Antibiotics for Post-Tonsillectomy Morbidity: Comparative Analysis of a Single Institutional Experience

机译：扁桃体切除术后发病率的抗生素：单一机构经验的比较分析

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Background: We have conducted this study to evaluate the effect of antibiotics, whether oral or intravenous, compared to no antibiotic protocol on post-tonsillectomy morbidity.Methods: A total of 270 patients aged 3 - 12 years were included in the study. Patients were assigned into three groups randomly; each group consisted of 90 patients. In the first group (group A), patients were given intravenous injections of ceftriaxone 50 mg/kg/24 hours in divided doses, the second group (group B) received oral co-amoxiclav (dose according to weight) for 5 days post-operatively, and in the third group, patients were not given antibiotics. Patients were evaluated for the incidence of any bleeding, number of days before resuming normal diet, incidence of nausea and vomiting, incidence of abdominal pain, frequency of analgesic use in the first week, and pain.Results: Our study groups were comparable in age, gender, and weight. There were no statistically significant differences between our study groups with regard to the incidence of post-tonsillectomy bleeding, time relapsed to resume normal diet, and pain score scale. Incidence of nausea, vomiting, and abdominal pain was more in the oral antibiotic group, and it was statistically significant.Conclusion: We do not recommend the routine use of antibiotics in post-tonsillectomy period in pediatric age group and oral antibiotics prove to have worse outcome with regard to the incidence of nausea, vomiting, and abdominal pain, and these recommendations need to be evaluated by multicenter evaluation.J Clin Med Res. 2016;8(5):385-388doi: http://dx.doi.org/10.14740/jocmr2523w
机译：背景：我们进行了这项研究，以评估与不使用抗生素方案相比，口服或静脉使用抗生素对扁桃体切除术后的发病率的影响。方法：本研究共纳入270名3-12岁的患者。将患者随机分为三组。每组由90名患者组成。在第一组（A组）中，患者以分次剂量静脉注射头孢曲松50 mg / kg / 24小时，第二组（B组）在术后5天接受口服Coamoxiclav（根据体重的剂量）在手术中，第三组患者未给予抗生素。对患者进行任何出血的发生率，恢复正常饮食的天数，恶心和呕吐的发生率，腹痛的发生率，第一周使用止痛药的频率以及疼痛的评估。结果：我们的研究组在年龄上具有可比性，性别和体重。在扁桃体切除术后出血的发生率，恢复正常饮食的复发时间以及疼痛评分量表方面，我们的研究组之间没有统计学上的显着差异。口服抗生素组恶心，呕吐和腹痛的发生率更高，且具有统计学意义。结论：我们不建议小儿年龄组在扁桃体切除术后定期使用抗生素，事实证明口服抗生素的病情较差关于恶心，呕吐和腹痛发生率的预后，这些建议需要通过多中心评估进行评估。JClin Med Res。 2016; 8（5）：385-388doi：http://dx.doi.org/10.14740/jocmr2523w

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