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Researchers’ and Clinicians’ Perceptions of Recruiting Participants to Clinical Research: A Thematic Meta-Synthesis

机译:研究人员和临床医生对招募参加临床研究的人员的看法:主题元合成

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Background: Recruiting the desired number of research participants is frequently problematic with resulting financial and clinical implications. The views of individuals responsible for participant recruitment have not been previously reviewed. This systematic review and thematic meta-synthesis explores researchers’ and clinicians’ experiences and perceptions of recruiting participants to clinical research, with the aim of informing improved recruitment systems and strategies. Methods: Studies published between January 1995 and May 2013 were identified from: Ovid MEDLINE, Ovid EMBASE, Ovid PSYCHINFO, ASSIA, British Nursing Index, Scopus, Web of Science, CINAHL and PubMed. Included studies were original peer reviewed research, with qualitative methodologies and an aim of exploring the views of clinicians and/or researchers on recruitment to clinical research. Studies discussing the recruitment of patients unable to give informed consent were excluded. The findings sections of the relevant studies were free coded to identify key concepts which were grouped into hierarchical themes. The quality of the identified studies was assessed and the relative contribution of each paper was checked to ensure individual studies did not dominate in any theme. Results: Eighteen relevant papers were identified which examined the views of researchers and clinicians in 10 clinical specialties. Five main themes emerged: building a research community, securing resources, the nature of research, professional identities and recruitment strategies. The views of researchers and clinicians were similar, although the role of ‘researcher’ was inconsistently defined. Conclusions: The general experience of recruiting participants to clinical research was one of competition and compromise. Competition arose over funding, staffing and participants, and between clinical and research responsibilities. Compromise was needed to create study designs that were acceptable to patients, clinicians and researchers. Forging relationships between clinical and research teams featured extensively, however the involvement of patients and the public within the research community was rarely discussed.J Clin Med Res. 2014;6(3):162-172doi: http://dx.doi.org/10.14740/jocmr1619w
机译:背景:招聘所需数量的研究参与者通常会在财务和临床意义上产生问题。先前尚未审查负责招募参与者的个人的观点。这项系统的综述和主题元综合研究,旨在研究人员和临床医生招募临床研究参与者的经验和看法,以期为改进的招募制度和策略提供信息。方法:1995年1月至2013年5月之间发表的研究资料来自:Ovid MEDLINE,Ovid EMBASE,Ovid PSYCHINFO,ASSIA,英国护理指数,Scopus,Web of Science,CINAHL和PubMed。包括的研究是原始的同行评审研究,采用定性方法,旨在探讨临床医生和/或研究人员对招募临床研究的看法。排除了征募无法征得知情同意的患者的研究。相关研究的发现部分进行了免费编码,以识别归类为分层主题的关键概念。评估已鉴定研究的质量,并检查每篇论文的相对贡献,以确保个别研究在任何主题中均不占主导地位。结果:鉴定出18篇相关论文,研究了10个临床专业的研究人员和临床医生的观点。出现了五个主要主题:建立研究社区,确保资源,研究的性质,专业身份和招聘策略。尽管“研究人员”的角色定义不一致,但研究人员和临床医生的观点相似。结论:招募临床研究参与者的一般经验是竞争和妥协之一。竞争在资金,人员和参与者以及临床和研究职责之间展开。需要做出折衷的做法来创建患者,临床医生和研究人员可以接受的研究设计。临床团队和研究团队之间的锻造关系广泛存在,但是很少讨论患者和公众在研究社区中的参与。JClin Med Res。 2014; 6(3):162-172doi:http://dx.doi.org/10.14740/jocmr1619w

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