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Prevalence of Acute Coronary Syndrome in Patients Suspected for Pulmonary Embolism or Acute Aortic Syndrome: Rationale for the Triple Rule-Out Concept

机译:怀疑患有肺栓塞或急性主动脉综合征的患者的急性冠状动脉综合征的患病率:三重排除概念的基础

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Background: The aims of the study were to evaluate the prevalence of acute coronary syndrome (ACS) among patients presenting with atypical chest pain who are evaluated for acute aortic syndrome (AAS) or pulmonary embolism (PE) with computed tomoangiography (CTA) and discuss the rationale for the use of triple rule-out (TRO) protocol for triaging these patients.Methods: This study is a retrospective analysis of patients presenting with atypical chest pain and evaluated with thoracic (CTA), for suspicion of AAS/PE. Two physicians reviewed patient files for demographic characteristics, initial CT and final clinical diagnosis. Patients were classified according to CTA finding into AAS, PE and other diagnoses and according to final clinical diagnosis into AAS, PE, ACS and other diagnoses.Results: Four hundred and sixty-seven patients were evaluated: 396 (84.8%) patients for clinical suspicion of PE and 71 (15.2%) patients for suspicion of AAS. The prevalence of ACS and AAS was low among the PE patients: 5.5% and 0.5% respectively (P = 0.0001), while the prevalence of ACS and PE was 18.3% and 5.6% among AAS patients (P = 0.14 and P = 0.34 respectively).Conclusion: The prevalence of ACS and AAS among patients suspected clinically of having PE is limited while the prevalence of ACS and PE among patients suspected clinically of having AAS is significant. Accordingly patients suspected for PE could be evaluated with dedicated PE CTA while those suspected for AAS should still be triaged using TRO protocol.J Clin Med Res. 2015;7(8):627-631doi: http://dx.doi.org/10.14740/jocmr2197w
机译:背景:本研究的目的是评估表现为非典型胸痛的急性冠状动脉综合征(ACS)的患病率,并通过计算机断层血管造影(CTA)对急性主动脉综合征(AAS)或肺栓塞(PE)进行评估,并进行讨论方法:本研究是对表现为非典型性胸痛并经胸部(CTA)评估的患者进行AAS / PE怀疑的回顾性分析。两位医生检查了患者档案的人口统计学特征,初始CT和最终临床诊断。根据CTA将患者分为AAS,PE和其他诊断,并根据最终临床诊断将其分类为AAS,PE,ACS和其他诊断。结果:评估了467例患者:396例(84.8%)临床怀疑有PE和71名(15.2%)患者怀疑AAS。 PE患者的ACS和AAS患病率较低:分别为5.5%和0.5%(P = 0.0001),而AAS患者的ACS和PE患病率分别为18.3%和5.6%(分别为P = 0.14和P = 0.34)结论:临床怀疑患有PE的患者中ACS和AAS的患病率有限,而临床怀疑患有AAS的患者中ACS和PE的患病率却很显着。因此,怀疑患有PE的患者可以接受专门的PE CTA评估,而怀疑患有AAS的患者仍应使用TRO方案进行分类。 2015; 7(8):627-631doi:http://dx.doi.org/10.14740/jocmr2197w

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