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首页> 外文期刊>Journal of Clinical Medicine Research >Summary of Glaucoma Diagnostic Testing Accuracy: An Evidence-Based Meta-Analysis
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Summary of Glaucoma Diagnostic Testing Accuracy: An Evidence-Based Meta-Analysis

机译：青光眼诊断测试准确性摘要：基于证据的荟萃分析

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Background: New glaucoma diagnostic technologies are penetrating clinical care and are changing rapidly. Having a systematic review of these technologies will help clinicians and decision makers and help identify gaps that need to be addressed. This systematic review studied five glaucoma technologies compared to the gold standard of white on white perimetry for glaucoma detection.Methods: OVID? interface: MEDLINE? (In-Process & Other Non-Indexed Citations), EMBASE?, BIOSIS Previews?, CINAHL?, PubMed, and the Cochrane Library were searched. A gray literature search was also performed. A technical expert panel, information specialists, systematic review method experts and biostatisticians were used. A PRISMA flow diagram was created and a random effect meta-analysis was performed.Results: A total of 2,474 articles were screened. The greatest accuracy was found with frequency doubling technology (FDT) (diagnostic odds ratio (DOR): 57.7) followed by blue on yellow perimetry (DOR: 46.7), optical coherence tomography (OCT) (DOR: 41.8), GDx (DOR: 32.4) and Heidelberg retina tomography (HRT) (DOR: 17.8). Of greatest concern is that tests for heterogeneity were all above 50%, indicating that cutoffs used in these newer technologies were all very varied and not uniform across studies.Conclusions: Glaucoma content experts need to establish uniform cutoffs for these newer technologies, so that studies that compare these technologies can be interpreted more uniformly. Nevertheless, synthesized data at this time demonstrate that amongst the newest technologies, OCT has the highest glaucoma diagnostic accuracy followed by GDx and then HRT.J Clin Med Res. 2016;8(9):641-649doi: http://dx.doi.org/10.14740/jocmr2643wCorrection in J Clin Med Res. 2017;9(3):231, doi: https://doi.org/10.14740/jocmr2643wc1
机译：背景：新的青光眼诊断技术正在渗透临床护理并且正在迅速变化。对这些技术进行系统的审查将有助于临床医生和决策者，并帮助确定需要解决的差距。这项系统的综述研究了五种青光眼技术，并将其与白/白视野检查的金标准进行了比较，以检测青光眼。方法：OVID？界面：MEDLINE？ （进行中的和其他非索引引文），EMBASE？，BIOSIS Previews？，CINAHL？，PubMed和Cochrane库进行了搜索。还进行了灰色文献检索。使用了技术专家小组，信息专家，系统评价方法专家和生物统计学家。建立了PRISMA流程图并进行了随机效应荟萃分析。结果：筛选了2,474篇文章。使用倍频技术（FDT）（诊断比值比（DOR）：57.7），其次是黄色/蓝色视野检查（DOR：46.7），光学相干断层扫描（OCT）（DOR：41.8），GDx（DOR： 32.4）和海德堡视网膜断层扫描（HRT）（DOR：17.8）。最令人担忧的是，异质性测试都在50％以上，这表明这些新技术中使用的临界值差异很大且在研究之间不一致。结论：青光眼内容专家需要为这些新技术建立统一的临界值，以便进行研究比较这些技术可以更统一地解释。尽管如此，目前的综合数据表明，在最新技术中，OCT具有最高的青光眼诊断准确性，其次是GDx，然后是HRT。JClin Med Res。 2016; 8（9）：641-649doi：http://dx.doi.org/10.14740/jocmr2643w在J Clin Med Res。 2017; 9（3）：231，doi：https://doi.org/10.14740/jocmr2643wc1

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