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首页> 外文期刊>Journal of Clinical Medicine Research >Gastrointestinal Bleeding in Patients With Acute Respiratory Distress Syndrome: A National Database Analysis
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Gastrointestinal Bleeding in Patients With Acute Respiratory Distress Syndrome: A National Database Analysis

机译:急性呼吸窘迫综合征患者的胃肠道出血:国家数据库分析

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Background: The goal of our study was to determine the impact of gastrointestinal bleeding (GIB) on in-hospital outcomes among acute respiratory distress syndrome (ARDS) patients, and subsequently determine the potential risk factors for the development of GIB. Methods: ARDS patients with and without GIB were identified using the National Inpatient Sample (2002 - 2012). Linear regression analysis was used to assess impact of GIB on in-hospital mortality, length of stay and total charges. Univariate logistic regression was used to determine associated odds ratios (OR) for causes of ARDS and common comorbid conditions. Results: We identified 149,190 ARDS patients. The incidence of GIB was the highest among patients 60 years (P 0.001). GIB was associated with longer hospitalization days (7.3 days versus 11.9 days, P 0.001), higher mortality (11% versus 27%, P 0.001) and greater economic burden ($82,812 versus $45,951, P 0.001). GIB was common in cirrhosis (OR: 8.3), peptic ulcer disease (OR: 3.7), coagulopathy disorders (OR: 3.003), thrombocytopenia (OR: 2.6), anemia (OR: 2.5) and atrial fibrillation (OR: 1.5). ARDS secondary to aspiration pneumonia (OR: 2.0), pancreatitis (OR: 2.0), sepsis (OR: 1.6) and community acquired pneumonia (OR: 0.8) was more likely to have GIB. Conclusion: Our study demonstrates that GIB in ARDS patients is associated with significant increased mortality, hospitalization and health care cost.
机译:背景:我们研究的目的是确定胃肠道出血(GIB)对急性呼吸窘迫综合征(ARDS)患者的院内预后的影响,并随后确定发展GIB的潜在危险因素。方法:使用国家住院患者样本(2002年至2012年)鉴定患有和不患有GIB的ARDS患者。线性回归分析用于评估GIB对住院死亡率,住院时间和总费用的影响。单因素逻辑回归用于确定ARDS病因和常见合并症的相关比值比(OR)。结果:我们确定了149,190名ARDS患者。在> 60岁的患者中,GIB的发生率最高(P <0.001)。 GIB与住院天数较长(7.3天对11.9天,P <0.001),更高的死亡率(11%对27%,P <0.001)和更大的经济负担(82,812美元对45,951美元,P <0.001)相关。 GIB常见于肝硬化(OR:8.3),消化性溃疡疾病(OR:3.7),凝血功能障碍(OR:3.003),血小板减少症(OR:2.6),贫血(OR:2.5)和心房颤动(OR:1.5)。继发于吸入性肺炎(OR:2.0),胰腺炎(OR:2.0),败血症(OR:1.6)和社区获得性肺炎(OR:0.8)的ARDS更可能患有GIB。结论:我们的研究表明,ARDS患者的GIB与死亡率,住院和医疗费用的显着增加有关。

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