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首页> 外文期刊>Journal of Clinical Medicine Research >Prevalence of Documented Excessive Weight Gain Among Adolescent Girls and Young Women Using Depot Medroxyprogesterone Acetate
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Prevalence of Documented Excessive Weight Gain Among Adolescent Girls and Young Women Using Depot Medroxyprogesterone Acetate

机译：在使用甲羟孕酮醋酸酯的青春期女孩和年轻女性中，有记录的体重过度增加的患病率

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Background: Depot medroxyprogesterone acetate (DMPA) is an accessible contraception with high efficacy among adolescents. However, concern of weight gain can impede DMPA use. The objective of this study was to determine prevalence of excessive weight gain associated with DMPA injection in young women and its predicting factor. Methods: This retrospective chart review included young women aged 10 - 24 years who had used DMPA and attended at Family Planning and Reproductive Medicine Unit, Siriraj Hospital for at least 6-month period during January 2010 to June 2016. Baseline clinical data, weight at beginning of contraception, and weight at 6 and 12 months thereafter were reviewed. Excessive weight was defined as weight gain of 5% of their baseline weight at 6 months. Various baseline variables were compared between groups with and without excessive weight gain. Results: Among 231 DMPA users in this study, there were 28 women (12.1%, 95% confidence interval (CI): 7.8 - 16.3) who had an excessive weight gain at 6 months. Age, baseline body mass index, or race did not affect the likelihood of excessive weight gain. The excessive weight gain group had significant higher proportion of nulliparity, unmarried status and DMPA-ever used history compared to another one. Six of 13 (46.2%) excessive weight gainers at 6 months who continued DMPA use had gain even more weight ( 10% of their baseline weigh) at 12 months. Conclusions: The majority of adolescent girls using DMPA had no excessive weight gain in 6 months. However, DMPA users who had excessive weight at 6 months were at high risk of gaining even more weight at 1 year.
机译：背景：醋酸甲羟孕酮（DMPA）是一种易于使用的避孕方法，在青少年中疗效很高。但是，担心体重增加会阻碍DMPA的使用。这项研究的目的是确定年轻妇女与DMPA注射相关的体重增加过多的发生率及其预测因素。方法：该回顾性图表回顾纳入了2010年1月至2016年6月期间使用DMPA并在Siriraj医院计划生育和生殖医学科治疗至少6个月的10至24岁的年轻女性。基线临床数据，体重开始避孕，并在之后的6和12个月进行体重检查。体重过多定义为在6个月时体重增加>基线体重的5％。比较体重增加和不增加的各组之间的各种基线变量。结果：在这项研究的231位DMPA用户中，有28位女性（12.1％，95％置信区间（CI）：7.8-16.3）在6个月时体重增加过多。年龄，基线体重指数或种族不会影响体重增加过多的可能性。与另一组相比，体重增加过多组的无效率，未婚状态和曾经使用过DMPA的病史比例要高得多。在13个月后继续使用DMPA的13名体重增加者中有6名（46.2％）在12个月时增加了更多体重（>基线体重的10％）。结论：大多数使用DMPA的青春期女孩在6个月内体重没有增加。但是，DMPA使用者在6个月时体重过重，则在1年时体重增加的风险很高。

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