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首页> 外文期刊>Journal of Clinical Medicine Research >Prognostic Factors of Functional Outcome Assessed by Using the Modified Rankin Scale in Subacute Ischemic Stroke
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Prognostic Factors of Functional Outcome Assessed by Using the Modified Rankin Scale in Subacute Ischemic Stroke

机译：改良Rankin量表评估亚急性缺血性卒中的功能预后因素

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Background: Most stroke survivors spent their lifetime with disability which not only affects the clients themselves and the family but also brings economic cost to the country. Therefore, this retrospective cohort study aimed to identify independent prognostic determinants associated with functional recovery in ischemic stroke within 6 months after onset. Methods: Data from all first-onset ischemic stroke patients admitted to the acute stroke unit of the tertiary, university hospital were reviewed for 5 years consecutively. The functional outcome of the patients was recorded during 6-month follow-up by using the modified Rankin Scale (mRS). Baseline characteristics, motor assessment and all stroke-related variables were assessed during first week after stroke and 6-month follow-up. In order to derive clinical predictors, the backward stepwise multivariable risk regression analyses were used with the generalized linear model. Results: The result revealed that in the 358 patients recruited into this study, 255 (71.2%) were in the functional recovery group (mRS score of 1 - 3) within 6 months after onset. The final model of multivariable risk regression analysis, with generalized linear model, demonstrated that the independent variables of functional recovery were leg score with a risk ratio (RR = 1.92, 95% confidence interval (CI): 1.14 - 3.21, P = 0.013), arm score (RR = 1.75, 95% CI: 1.02 - 3.01, P = 0.042) and age older than 75 years (RR = 1.36, 95% CI: 1.04 - 1.77, P = 0.025). Conclusions: Achieving functional recovery during 6 months post stroke was related to age and motor improvement. With limited resources, continuity of rehabilitation training in the community system or allocation of caregiver training should be a part of discharge planning to promote recovery.
机译：背景：大多数中风幸存者终生患有残疾，这不仅影响了客户自己和家庭，而且给国家带来了经济损失。因此，这项回顾性队列研究旨在确定与发作后6个月内缺血性卒中功能恢复相关的独立预后决定因素。方法：连续5年对来自三级大学医院急性​​卒中病房的所有首次发作的缺血性卒中患者的数据进行回顾。使用改良的兰金量表（mRS）在6个月的随访期间记录了患者的功能结局。在卒中后的第一周和6个月的随访中评估基线特征，运动评估和所有与卒中相关的变量。为了得出临床预测指标，将后向逐步多元风险回归分析与广义线性模型一起使用。结果：结果显示，在入组本研究的358例患者中，发病后6个月内功能恢复组（mRS评分1-3）中有255例（71.2％）。最终的多变量风险回归分析模型（具有广义线性模型）表明，功能恢复的独立变量是腿部得分，风险率（RR = 1.92，95％置信区间（CI）：1.14-3.21，P = 0.013） ，手臂得分（RR = 1.75，95％CI：1.02-3.01，P = 0.042）和年龄大于75岁的年龄（RR = 1.36，95％CI：1.04-1.77，P = 0.025）。结论：卒中后6个月内功能恢复与年龄和运动能力改善有关。在资源有限的情况下，社区系统中康复培训的连续性或护理人员培训的分配应成为出院计划中促进康复的一部分。

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