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首页> 外文期刊>Journal of Clinical Medicine Research >Comparison of the Effectiveness of Hydroxyethyl Starch (Voluven) Solution With Normal Saline in Hemorrhagic Shock Treatment in Trauma
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Comparison of the Effectiveness of Hydroxyethyl Starch (Voluven) Solution With Normal Saline in Hemorrhagic Shock Treatment in Trauma

机译：羟乙基淀粉（Voluven）溶液与生理盐水在创伤性休克治疗中的疗效比较

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Background: Appropriate fluid therapy affects morbidity and mortality rates. A conclusion is yet to be reached on the role of crystalloids and colloids in immediate fluid therapy. This study was done to determine the suitable solution in immediate resuscitation of patients with hemorrhagic shock caused by tissue trauma.Methods: One hundred trauma patients with hemorrhagic shock, who underwent fluid therapy in the emergency unit, were assigned randomly to two groups of hydroxyethyl starch (Voluven) and normal saline. Before and after fluid therapy, 1 cc of blood was taken from all patients in order to determine and compare base excess levels.Results: In hydroxyethyl starch (Voluven) and normal saline groups, base excess level after solution therapy increased about 9.65 and 5.46 volumes, respectively, in which augmentation in hydroxyethyl starch (Voluven) group is significantly higher than normal saline group (P ≤ 0.001).Conclusion: By using hydroxyethyl starch (Voluven) for fluid therapy in hemorrhagic shock caused by trauma, serum base excess decreases and results in improvement in tissue perfusion and better balance in acid-base status and it seems to be superior over normal saline administration, but the building block of the ideal fluid therapy should still remain with the physician’s final clinical judgment.J Clin Med Res. 2016;8(11):815-818doi: http://dx.doi.org/10.14740/jocmr2702w
机译：背景：适当的输液治疗会影响发病率和死亡率。关于晶体和胶体在即时液体治疗中的作用尚未得出结论。这项研究旨在确定由组织创伤引起的失血性休克患者立即复苏的合适解决方案。方法：将在急诊室接受液体疗法的100例失血性休克创伤患者随机分配到两组羟乙基淀粉中（Voluven）和生理盐水。在液体疗法之前和之后，从所有患者中抽取1 cc血液以测定和比较基础过量水平。结果：在羟乙基淀粉（Voluven）和生理盐水组中，溶液疗法后基础过量水平增加了约9.65和5.46体积结论：羟乙基淀粉（Voluven）在创伤引起的失血性休克液体治疗中的作用明显高于生理盐水组（P≤0.001）。结果可改善组织灌注，并改善酸碱状态的平衡，似乎优于普通生理盐水给药，但理想的液体疗法的基础仍然应由医师做出最终临床判断。JClin Med Res。 2016; 8（11）：815-818doi：http://dx.doi.org/10.14740/jocmr2702w

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