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首页> 外文期刊>Journal of Chemistry >Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemical and In Vitro Biological Performances Studies
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Fabrication of Bilayer Coating of Poly(3,4-ethylenedioxythiophene)-Halloysite/Chitosan and Mg2+/Sr2+-Doped HAP on Titanium Alloy for Biomedical Implant Applications: Physicochemical and In Vitro Biological Performances Studies

机译：用于生物医学植入物的钛合金上的（3,4-乙撑二氧噻吩）-Halloysite /壳聚糖和Mg2 + / Sr2 +掺杂的HAP双层涂层的制备：物理化学和体外生物学性能研究

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The prime objective of the present work is to develop biocompatible overlayer-deposited titanium alloys to replace already available titanium alloy-based biomaterials for implantation applications. Here, we prefer to use a bilayer coating on titanium alloys instead of single coating. The adhesion and biocompatibility of titanium alloy is improved by coating with a bilayer, for example, PEDOT-HNT/CS-MHA composite using the electrochemical deposition method. Corrosion behavior of the PEDOT-HNT/CS-MHA bilayer composite coating was investigated in the PBS medium by polarization studies. The functional groups, phase purity, surface morphology, and wettability of the PEDOT-HNT/CS-MHA were characterized by various instrumental techniques like FTIR, XRD, SEM, and contact angle techniques. From the above studies, it is proved that PEDOT-HNT/CS-MHA-coated Ti alloy showing a better biocompatibility and corrosion resistance than the PEDOT-HNT-deposited Ti alloy. In addition, the in vitro bactericidal and cell viability studies were also carried out to further confirm the biocompatibility of the protective coating. Hence, the bilayer deposition has shown excellent stability and biocompatibility and can be used for the potential biomaterials for orthopedics applications.
机译：本工作的主要目的是开发生物相容性的覆盖层沉积钛合金，以取代已经可用的钛合金基生物材料用于植入应用。在这里，我们更喜欢在钛合金上使用双层涂层，而不是单层涂层。钛合金的粘附性和生物相容性可通过使用电化学沉积方法涂上双层涂层（例如PEDOT-HNT / CS-MHA复合材料）来改善。通过极化研究，研究了PEDOT-HNT / CS-MHA双层复合涂层在PBS介质中的腐蚀行为。 PEDOT-HNT / CS-MHA的官能团，相纯度，表面形态和润湿性通过各种仪器技术（如FTIR，XRD，SEM和接触角技术）进行了表征。通过以上研究，证明了PEDOT-HNT / CS-MHA涂层的Ti合金比PEDOT-HNT沉积的Ti合金具有更好的生物相容性和耐腐蚀性。此外，还进行了体外杀菌和细胞活力研究，以进一步确认保护涂层的生物相容性。因此，双层沉积已显示出极好的稳定性和生物相容性，可用于骨科应用的潜在生物材料。

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