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首页> 外文期刊>Journal of Clinical Medicine and Research >Susceptibility of nosocomial Staphylococcus aureus, Escherichia coli and Candida albicans to some antimicrobial drugs routinely used in Adamawa State Hospitals, Nigeria
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Susceptibility of nosocomial Staphylococcus aureus, Escherichia coli and Candida albicans to some antimicrobial drugs routinely used in Adamawa State Hospitals, Nigeria

机译：医院金黄色葡萄球菌，大肠杆菌和白色念珠菌对尼日利亚阿达玛瓦州立医院常规使用的某些抗菌药物的敏感性

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The presence of pathogenic?Escherichia coli,?Staphylococcus aureus?and?Candida albicans?causing nosocomial infections to hospitalized patients in four large State hospitals in Adamawa State was investigated for a period of two and half years. One hundred and sixty isolates of each organism were collected from clinical specimens obtained from patients admitted into the hospitals for reasons other than the infection caused by these organisms. Though from each hospital 160 isolates of each organism were collected, there were some variations in the proportions of isolates collected per site at p < 0.05 level of significance. For?E. coli, 27.5% isolates were obtained from surgical wound and urinary tract sites.?C. albicans?was the most common organism associated with urinary tract (35 - 42.5%) and catheter site infections (20 - 25%). Majority of?S. aureus?isolates obtained were from skin and soft tissue infections (25 - 35%). Antimicrobial susceptibility tests of the isolates performed by the disk diffusion method gave variable results. In case of?E. coli,resistance to ampicillin (80%) and tetracycline (82.5%) were particularly high in Specialist Hospital, Yola (SHY), than the other hospitals.?The susceptibility data showed that?S. aureus?isolated from Specialist Hospital Yola (SHY) was resistant to penicillin (65%), ampicillin (77.5%) and tetracycline (72.5%). In this study, a significant number of isolates of?C. albicans?isolated from Specialist Hospital Yola (SHY), were resistant to miconazole (32.5%), nystatin (30%) and itraconazole (27.5%). The study showed that there are some microorganisms causing nosocomial infections and are not susceptible to some antimicrobial drugs commonly used in the hospitals in Adamawa State, Nigeria. Proportion of the isolates susceptible to antimicrobial drugs depend on the size of the hospital and the type of medical procedures performed in the hospital.
机译：在阿达玛瓦州的四家大型国立医院中，调查了导致医院感染的病原性大肠杆菌，金黄色葡萄球菌和白色念珠菌的存在，为期两年半。从除由于这些微生物引起的感染以外的其他原因入院的患者的临床标本中收集每种微生物的160株分离株。尽管从每家医院收集了160种每种生物的分离株，但每个站点收集的分离株的比例在p <0.05的显着水平上仍存在一些差异。前面。大肠埃希菌，从手术伤口和尿路部位获得了27.5％的分离株。白色念珠菌是最常见的与尿道（35-42.5％）和导管部位感染（20-25％）相关的生物。多数？获得的金黄色葡萄球菌分离物来自皮肤和软组织感染（25-35％）。通过圆盘扩散法对分离物进行的药敏试验表明结果不一。如果是？在Yola（SHY）的专科医院中，大肠埃希菌对氨苄青霉素（80％）和四环素（82.5％）的耐药性特别高。分离自尤拉专科医院（SHY）的金黄色葡萄球菌对青霉素（65％），氨苄青霉素（77.5％）和四环素（72.5％）有抵抗力。在这项研究中，有大量的？C分离株。从尤拉专科医院（SHY）分离出的白色念珠菌对咪康唑（32.5％），制霉菌素（30％）和伊曲康唑（27.5％）有抵抗力。研究表明，有一些微生物会引起医院感染，并且不易受到尼日利亚阿达玛瓦州医院常用的某些抗菌药物的影响。对抗菌药物敏感的分离株的比例取决于医院的规模和在医院进行的医疗程序的类型。

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