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Neonatal jaundice: Prevalence and associated factors as seen in Federal Medical Centre Abakaliki, Southeast Nigeria

机译:新生儿黄疸:在尼日利亚东南部阿巴卡利基联邦医疗中心的患病率及相关因素

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To determine the occurence, aetiological and other associated factors of neonatal jaundice in Federal Medical Centre Abakaliki, Southeast Nigeria with a view to determining strategies for prevention, using patients’ and maternal case folders and Neonatal Intensive Care Unit (NICU) admission register, all cases of neonatal jaundice (NNJ) admitted to Federal Medical Centre, Abakaliki from January 1st?2008 to December 31st?2009 were retrospectively studied. The study revealed that NNJ accounted for 35% of all NICU admissions. The leading aetiological factors of NNJ were septicaemia (32.5%) and prematurity (17.5%). Significant bilirubinaemia, septicaemia, contact with naphthalene ball contaminated clothes occurred significantly more in the outborn than in the inborn babies 40(48.2%) vs 66(63%) p = 0.000, 33(50%) vs 17(42.5) p = 0.046, 6(9.1%) vs 0(0.0%) p = 0.045 respectively. Significantly more mothers of outborn than of inborn babies were unbooked and took herbal medications in pregnancy. Overwhelming majority of the subjects (89.6%) developed jaundice within the 1st week of life. Significantly more inborn than outborn were preterm and exclusively breastfed, 25(30.1%) vs 14(19.7%) p = 0.001; 75(90.4%) vs 9(12.7%) p = 0.000 respectively. Also, significantly more outborn than inborn babies had exchange blood transfusion and kernicterus, 27(38%) vs 5(6%) p = 0.000; 14(19.7%) vs 1(1.2%) p = 0.000 respectively. Hence, there is need for sustained education of the general populace on the essence of regular antenatal supervision of pregnancy and delivery in appropriate health care facility to ultimately curb the incidence of severe NNJ.
机译:为了确定尼日利亚东南部联邦医学中心阿巴卡利基联邦医学中心新生儿黄疸的发生,病因及其他相关因素,以便确定预防策略,使用患者和产妇病例文件夹以及新生儿重症监护病房(NICU)入院登记册,所有病例回顾性分析了2008年1月1日至2009年12月31日在阿巴卡利基联邦医疗中心收治的新生儿黄疸的病情。研究显示,NNJ占所有重症监护病房录取的35%。 NNJ的主要病因是败血症(32.5%)和早产(17.5%)。新生儿中明显的胆红素血症,败血病,与萘球污染的衣服接触比新生儿明显多于40(48.2%)vs 66(63%)p = 0.000、33(50%)vs 17(42.5)p = 0.046 ,分别为6(9.1%)和0(0.0%)p = 0.045。未预订并在怀孕期间服用草药的外来母亲要多于新生儿。绝大多数受试者(89.6%)在生命的第一周内出现了黄疸。早产和纯母乳喂养的婴儿明显多于出生婴儿,分别为25(30.1%)和14(19.7%)p = 0.001; 75(90.4%)vs 9(12.7%)p = 0.000。此外,换血和结石的婴儿比出生婴儿多得多,分别为27(38%)和5(6%)p = 0.000; 14(19.7%)与1(1.2%)p = 0.000。因此,有必要对普通民众进行持续的教育,以在适当的卫生保健机构中定期对产前妊娠进行监督,并最终在适当的卫生保健机构进行分娩,以最终控制严重的NNJ发病率。

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