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首页> 外文期刊>Journal of Clinical Medicine Research >Comparative Changes in Tissue Oxygenation Between Laparoscopic and Open Cholecystectomy
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Comparative Changes in Tissue Oxygenation Between Laparoscopic and Open Cholecystectomy

机译：腹腔镜和开腹胆囊切除术之间组织氧合的比较变化

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Background: Previous studies examined the effect of laparoscopic cholecystectomy (LC) versus open cholecystectomy (OC) on physiological variables of the respiratory system. In this study we compared changes in arterial blood gases-related parameters between LC and OC to assess their comparative influence on gas exchange.Methods: We studied 28 patients, operated under identical anesthetic protocol (LC: 18 patients, OC: 10 patients). Measurements were made on the morning before surgery (BS), the second (AS2) and the eighth (AS8) postoperative day. Studied parameters, including alveolar-arterial difference in PO2 ((A-a)DO2) and oxygen content (Oct in vol%), were statistically compared.Results: On AS2 a greater increase was found in ((A-a)DO2) for the OC compared to LC (4.673 ± 0.966 kPa versus 3.773 ± 1.357 kPa, respectively). Between BS and AS2, Oct in vol% decreased from 17.55 ± 1.90 to 15.69 ± 1.88 in the LC and from 16.99 ± 2.37 to 14.62 ± 2.23 in the OC, whilst a reduction (P = 0.093) between AS2 and AS8 was also found for the open method. Besides, on AS2, SaO2% decrease was greater in OC compared to LC (P = 0.096).Conclusions: On AS2, the greater increase in OC-((A-a)DO2) associated with Oct in vol% and SaO2% findings also in OC group suggest that LC might be associated with lower risk for impaired tissue oxygenation.J Clin Med Res. 2015;7(4):232-241doi: http://dx.doi.org/10.14740/jocmr2086w
机译：背景：以前的研究检查了腹腔镜胆囊切除术（LC）与开腹胆囊切除术（OC）对呼吸系统生理变量的影响。在这项研究中，我们比较了LC和OC之间动脉血气相关参数的变化，以评估它们对气体交换的比较影响。方法：我们研究了28例在相同麻醉方案下手术的患者（LC：18例，OC：10例）。在手术前的早晨（BS），术后第二天（AS2）和第八天（AS8）进行测量。统计比较研究的参数，包括PO2的肺泡-动脉差异（（Aa）DO2）和氧含量（以体积％表示的Oct）。结果：与AS2相比，OC的（（Aa）DO2）的增加更大到LC（分别为4.673±0.966 kPa和3.773±1.357 kPa）。在BS和AS2之间，Oct的体积百分比在LC中从17.55±1.90降低到15.69±1.88，在OC中从16.99±2.37降低到14.62±2.23，同时AS2和AS8之间的降低也（P = 0.093）开放方法。此外，在AS2上，OC中SaO2％的降低幅度要比LC更大（P = 0.096）。结论：在AS2上，OC-（（Aa）DO2）与Oct的vol％和SaO2％的升高幅度也更大。 OC组建议LC可能与较低的组织氧合受损风险有关。JClin Med Res。 2015; 7（4）：232-241doi：http://dx.doi.org/10.14740/jocmr2086w

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