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首页> 外文期刊>Journal of Clinical Medicine and Research >Body mass index (BMI) related insulin resistance in polycystic ovarian syndrome among patients referred to gynecology clinic of Imam Reza Hospital, Tehran, Iran
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Body mass index (BMI) related insulin resistance in polycystic ovarian syndrome among patients referred to gynecology clinic of Imam Reza Hospital, Tehran, Iran

机译：伊朗德黑兰伊玛目·雷扎医院妇科门诊的多囊卵巢综合征患者中与体重指数（BMI）相关的胰岛素抵抗

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Polycystic ovarian syndrome (PCOs) is one of the commonest endocrinopathies of women. The present work has been undertaken with an aim to study insulin resistance rate among army personnel families. Out of 108 women suffering from oligomenorrhea and hirsutism referred to gynecology clinic of Imam Reza hospital from 2009 to 2010, 58 patients with PCOs were evaluated for insulin resistance. Their disease was diagnosed clinically and confirmed by laboratory findings. The patients fasting blood sugar (FBS) was measured to be 81 to 103 with mean of 91.44 ± 6.52. Insulin level of their fasting blood (FBI) was 3.1 to 33 with mean of 10.95 ± 7.53. FBS/FBI ratio ranged from 2.87 to 31.6 with mean of 12.54 ± 7.98. The co-relational analysis reveals a positive relationship between insulin resistance and?body mass index?(BMI; normal, overweight and obese). There was a significant association between these two ordinal variables (Spearman’s Correlation Coefficient is 0.59, P < 0.01). Leutinizing hormone/follicle stimulating hormone (LH/FSH) ratio is not significantly related with BMI (P = 0.65) and no significant relationship was observed between age groups and LH/FSH ratio (P = 0.76). The results achieved by two-way analysis of variance (ANOVA), that is, the F-values given in the Tests of Between-Subjects Effects indicate that the contribution of age group to ANOVA is not significant (F = 0.160, P = 0.852). The level of significance between BMI and FBS/FBI is 0.699 (F = 0.360). In addition to the main effects of both variables, there is no significant interaction. 6% of overweight and 39% of our obese patients were resistant to insulin, while no resistance to insulin was observed among cases with normal BMI.
机译：多囊卵巢综合征（PCO）是女性最常见的内分泌病变之一。目前的工作旨在研究陆军人员家庭中的胰岛素抵抗率。在2009年至2010年转诊至Imam Reza医院妇科诊所的108名患有少经和多毛症的妇女中，对58名PCO患者进行了胰岛素抵抗评估。他们的疾病被临床诊断并通过实验室检查结果得到证实。空腹血糖（FBS）的患者为81至103，平均值为91.44±6.52。空腹血（FBI）的胰岛素水平为3.1至33，平均值为10.95±7.53。 FBS / FBI比率范围从2.87到31.6，平均值为12.54±7.98。相互关系分析显示胰岛素抵抗与“体重指数”（BMI;正常，超重和肥胖）之间呈正相关。这两个序数变量之间存在显着关联（Spearman的相关系数为0.59，P <0.01）。促白激素/卵泡刺激素（LH / FSH）的比率与BMI无关（P = 0.65），年龄组和LH / FSH比率之间无显着关系（P = 0.76）。通过方差两因素分析（ANOVA）得出的结果，即受试者间效应测试中给出的F值表明，年龄组对ANOVA的贡献不显着（F = 0.160，P = 0.852 ）。 BMI和FBS / FBI之间的显着性水平为0.699（F = 0.360）。除了两个变量的主要影响外，没有明显的相互作用。 BMI正常的患者中，有6％的超重患者和39％的肥胖患者对胰岛素抵抗，而未观察到胰岛素抵抗。

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