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首页> 外文期刊>Journal of Clinical Medicine and Research >Recovery of sertoli cells by Allium cepa in Toxoplasma gondii infected rats
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Recovery of sertoli cells by Allium cepa in Toxoplasma gondii infected rats

机译：洋葱弓形虫感染弓形虫致大鼠睾丸支持细胞的恢复。

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Toxoplasma gondii?is a protozoan parasite that is globally widespread and it affects men and animals. We investigated the effect of allium cepa (onion juice) on sperm parameters, testestrone level in male rats was experimentally infected by?T. gondii.Wistar male rats (n=40) were allocated into four groups: control group (n=10), T1?group that received tachyzoites of?T. gondii?(n=10), T2?group that received tachyzoites of?T. gondii?plus fresh onion juice 1cc per rat daily by gavages method (n=10), and T3 group which received?fresh onion juice?1cc per rat daily by gavage method (n=10). 30 days after inducing toxoplasma, 5cc blood were collected for measuring testosterone. Testes tissues of rats in all groups were removed; then, they were prepared for sertoli cells analysis. Serum total testosterones and sertoli were ?significantly decreased in groups that were infected with?T. gondii, in comparison to control and onion groups. Moreover, comparing to control group (p<0.05), testes weights in toxoplasma group were drastically decreased. Since, in our study,?T.gondii?had grave effect on serum total testosterones, and because of applying fresh onion juice led to removing this harmful effect, it is suggested that eating of onion is useful in infected men.
机译：弓形虫是一种原生动物的寄生虫，在全球范围内广泛传播，影响人类和动物。我们研究了洋葱洋葱洋葱汁对精子参数的影响，雄性大鼠睾丸酮水平被ΔT实验感染。将Wistar雄性大鼠（n ＝ 40）分为四组：对照组（n ＝ 10），接受αT速殖子的T1β组。刚地（n = 10），T2组接受了ta的速殖子。灌肠法每只大鼠每天加新鲜洋葱汁1cc（n = 10），T3组灌胃法每只大鼠每天新鲜洋葱汁？1cc（n = 10）。诱导弓形虫后30天，收集5cc血液以测量睾丸激素。取各组大鼠睾丸组织。然后，准备将其用于sertoli细胞分析。感染ΔT的组中血清总睾丸激素和睾丸脂苷显着下降。与对照组和洋葱组相比。此外，与对照组相比，弓形虫组的睾丸重量显着降低（p <0.05）。由于在我们的研究中，“ T.gondii”对血清总睾丸激素有严重影响，并且由于使用新鲜的洋葱汁导致消除了这种有害作用，因此建议在受感染的男性中食用洋葱是有用的。

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