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首页> 外文期刊>Journal of Clinical Medicine and Research >Liquid nitrogen cryotherapy vs. Betamethasone lotion in the management of Alopecia areata
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Liquid nitrogen cryotherapy vs. Betamethasone lotion in the management of Alopecia areata

机译：液氮冷冻疗法与倍他米松乳液在斑秃的处理中

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摘要

Alopecia areata (AA) is a common disease of hair follicles. Cryotherapy has been employed to stimulate hair regrowth. We decided to evaluate the efficacy of this method in patchy AA. Forty patients of age >5 years?and with 120 recalcitrant patches were enrolled in this study. AA had covered less than 25% of patients’ scalps. In each individual, one lesion was treated with nitrogen cryotherapy once weekly for a period of 6 weeks; meanwhile another lesion was treated with topical 0.1% betamethasone lotion. All patients were followed up from weeks 2 to 14. Thirty-nine out of forty patients completed therapy. The overall response rate was 88% for patches treated with cryotherapy and 90% for patches treated with betamethasone lotion. Complete recovery (>90% terminal hair growth) was not obtained in any patient.? Chi-square test showed no significant difference between improvements of alopecia in the two groups (reliability 95%). Pearson measurement showed a significant reverse relationship between diameter and duration of patches and the improvement rate in both groups. Liquid nitrogen?cryotherapy can be a helpful modality in the treatment of AA.
机译：斑秃（AA）是毛囊的常见疾病。冷冻疗法已被用于刺激头发再生。我们决定评估该方法在斑块状AA中的功效。本研究招募了40名年龄大于5岁且有120例顽固性斑块的患者。机管局只覆盖了不到25％的患者头皮。在每个个体中，每周一次用氮气冷冻疗法治疗一个病变，持续6周。同时用局部0.1％倍他米松洗剂治疗另一个病变。从第2周到第14周对所有患者进行了随访。四十名患者中有三十九名完成了治疗。冷冻疗法治疗的贴剂的总缓解率为88％，倍他米松洗剂治疗的贴剂的总缓解率为90％。在任何患者中均未获得完全恢复（> 90％的末端毛发生长）。卡方检验显示两组的脱发改善之间无显着差异（可靠性95％）。皮尔森（Pearson）测量显示两组直径和贴剂持续时间与改善率之间存在显着的反向关系。液氮冷冻疗法可能是治疗AA的一种有用方式。

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