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首页> 外文期刊>Journal of Clinical Medicine Research >Co-Infections in Children Hospitalised for Bronchiolitis: Role of Roomsharing
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Co-Infections in Children Hospitalised for Bronchiolitis: Role of Roomsharing

机译：毛细支气管炎住院儿童的合并感染：客房共享的作用

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Background: Bronchiolitis is a major cause for hospitalisation in young children during the winter season, with respiratory syncytial virus (RSV) as the main causative virus. Apart from standard hygiene measures, cohorting of RSV-infected patients separately from RSV-negative patients is frequently applied to prevent cross-infection, although evidence to support this practice is lacking. The objective is to evaluate the risk of room sharing between RSV-positive and RSV-negative patients. Methods: We performed a prospective observational cohort study in children < 2 years hospitalised with acute bronchiolitis. During the first day of admission, patients shared one room, pending results of virological diagnosis (PCR). When diagnostic results were available, RSV-positive and RSV-negative patients were separated. Standard hygienic measures (gowns, gloves, masks, hand washing) were used in all patients. Results: We included 48 patients (83% RSV-positive). Co-infection was found in nine patients at admission, and two during hospitalisation (23%). The two patients with acquired co-infection had been nursed in a single room during the entire admission. None of 37 patients sharing a room with other bronchiolitis patients (20 with patients with a different virus) were co-infected during admission. Disease severity in co-infection was not worse than in mono-infection. Conclusion: One in five patients with bronchiolitis was co-infected, but co-infection acquired during admission was rare and was not associated with more severe disease. Room sharing between RSV-positive and RSV-negative patients (on the first day of admission) did not influence the risk of co-infection, suggesting that cohorting of RSV-infected patients separate from non-RSV-infected patients may not be indicated. doi: http://dx.doi.org/10.4021/jocmr1556w
机译：背景：毛细支气管炎是冬季住院的主要原因，呼吸道合胞病毒（RSV）是主要的致病病毒。除了标准的卫生措施外，经常采用将RSV感染患者与RSV阴性患者分开进行队列研究，以防止交叉感染，尽管缺乏支持这种做法的证据。目的是评估RSV阳性和RSV阴性患者之间共享房间的风险。方法：我们对住院急性呼吸道细支气管炎的2岁以下儿童进行了一项前瞻性观察队列研究。在入院的第一天，患者共享一个房间，等待病毒学诊断（PCR）结果。当获得诊断结果时，将RSV阳性和RSV阴性的患者分开。所有患者均采用标准卫生措施（礼服，手套，口罩，洗手）。结果：我们纳入了48位患者（83％RSV阳性）。入院时发现9例患者合并感染，住院期间发现2例（23％）。在整个入院期间，两名患有合并感染的患者已在一个房间内进行了护理。入院期间，与其他毛细支气管炎患者共用一个房间的37位患者（其中20位患有另一种病毒的患者）中没有人被共同感染。合并感染的疾病严重程度不比单一感染严重。结论：细支气管炎患者中有五分之一被合并感染，但在入院期间获得的合并感染很少，并且与更严重的疾病无关。 RSV阳性和RSV阴性患者之间的房间共享（在入院的第一天）不影响合并感染的风险，这表明可能不建议将RSV感染患者与未感染RSV的患者分开。 doi：http：//dx.doi.org/10.4021/jocmr1556w

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