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首页> 外文期刊>Journal of Clinical and Experimental Investigations >The evaluation of rubella and sitomegalovirus IgG avidity tests in pregnants: four-year experience
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The evaluation of rubella and sitomegalovirus IgG avidity tests in pregnants: four-year experience

机译：孕妇风疹和巨细胞病毒IgG亲和力测试的评估：四年经验

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Objective: In this study, we aim to evaluate the retrospective IgG avidity index (AI) test results of the pregnant, who have applied to our hospital and had pregnancy screening test and have been asked for rubella and cytomegalovirus antibody tests and IgG AI test in 4 year period. Methods: Anti-rubella IgM, anti-rubella IgG, anti-CMV IgM and anti-CMV antibodies were performed by IMMULITE 2000XPi? Immunoassay System (Siemens, Germany) whereas IgG AI tests were performed by commercial kits of rubella and cytomegalovirus antibody tests (Dia.Pro? Diagnostic, Milano-Italy). Results: Between January 2010 and December 2013, 23 (7.32 %) of 314 pregnant women tested rubella IgG AI had low AI, and 266 cases had high AI rate; 14 (17.28%) of 81 pregnant women tested CMV IgG AI, had lower AI rate, 52 of them had high AI. 9 out of 23 pregnant women, who were detected low rubella were requested only AI without any IgM and IgG value; the IgG antibody of 13 pregnant was reactive, and IgM antibody was not requested; IgG and IgM antibody of 1 pregnant was detected positive. When 5 pregnant, who were detected low CMV AI were requested AI without IgG and IgM value; the IgG and IgM of 4 was reactive; 4 of them had IgG reactive but IgM negative; 1 had IgG and IgM negative. Conclusion: As a result, our low rubella AI rate has been detected lower than the rates in our country since our study population contains only the pregnant. Our low CMV AI rate varies due to the same reasons as literature data. During pregnancy scanning, performing of AI testing together with specific IgG and IgM will save both time and will be more meaningful in clinical evaluation for pregnant women.
机译：目的：在这项研究中，我们旨在评估已在我院申请并进行了妊娠筛查并被要求进行风疹和巨细胞病毒抗体检测以及IgG AI检测的孕妇的回顾性IgG亲和力指数（AI）检测结果。 4年期限。方法：用IMMULITE 2000XPi进行抗风疹IgM，抗风疹IgG，抗CMV IgM和抗CMV抗体。免疫分析系统（德国，西门子），而IgG AI测试则通过风疹和巨细胞病毒抗体测试的商业试剂盒（Dia.Pro？Diagnostic，米兰意大利）进行。结果：2010年1月至2013年12月，在314名接受测试的风疹IgG AI孕妇中，有23名（7.32％）的AI较低，有266例AI的发生率较高; 81名孕妇中有14名（17.28％）检测了CMV IgG AI，其AI发生率较低，其中52名AI高。在检测到低风疹的23名孕妇中，有9名只要求提供AI，而没有任何IgM和IgG值; 13名孕妇的IgG抗体具有反应性，不需要IgM抗体; 1名孕妇的IgG和IgM抗体被检测为阳性。当有5名孕妇被检测出低CMV AI时，要求AI不含IgG和IgM值; IgG和IgM为4是反应性的;其中4个具有IgG反应性但IgM阴性; 1的IgG和IgM阴性。结论：结果，由于我们的研究人群仅包含孕妇，因此我们发现低的风疹AI发生率低于我们的国家。由于与文献数据相同的原因，我们较低的CMV AI率有所不同。在怀孕扫描期间，将AI测试与特定的IgG和IgM一起执行将节省时间，并且在孕妇临床评估中将更有意义。

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