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首页> 外文期刊>Journal of Clinical and Experimental Investigations >Intragastric manometric measurements of patients with hiatal hernia: A prospective controlled study
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Intragastric manometric measurements of patients with hiatal hernia: A prospective controlled study

机译：食管裂孔疝患者的胃内压力测量：一项前瞻性对照研究

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Objective: Hiatal hernia is a disorder in which abdominal contents, especially gastroesophageal junction and proximal stomach are displaced through an incompetent esophageal hiatus into mediastinum. Aim of this study is to investigate the relationship betweeen intragastric pressure and incompetent cardioesophageal sphincter and hiatal hernia.Methods: The sample is composed of 81 individuals; 51.9% of which are male (n: 42) and 48.1% of which are female (n: 39) with median age of 42.00. Two groups have been constituted: A control group of healthy volunteers (G1) and a patient group with hiatal hernia (G2). After gastroscopy, all patients and controls underwent gastric and esophageal manometry using a water perfused catheterResults: Mean intragastric pressure was 1,308 mmHg for G1 and, -0,105 mmHg for G2. Mean lower esophageal pressure were 13,143 mmHg and 11,65 mmHg, and upper esophageal pressure were 35,273 mmHg and 27,211 mmHg for G1 and G2, respectively. 24 hour pH metry test revealed 26.8% physiologic gastroesophageal reflux and 73.2% pathologic gastroesophageal reflux in G2. There were statistically significant difference between two groups for mean intragastric pressure (p Conclusion: This study shows that hiatal hernia results in significantly lower intragastric pressures
机译：目的：食管裂孔疝是一种疾病，其中腹部内容物，尤其是胃食管连接处和近端胃部通过无能的食管裂孔移位到纵隔。本研究的目的是探讨胃内压力与无能力的食管括约肌和食管裂孔疝的关系。其中男性占51.9％（n：42），女性占48.1％（n：39），中位年龄为42.00。分为两组：健康志愿者对照组（G1）和食管裂孔疝患者组（G2）。胃镜检查后，所有患者和对照组均使用注水导管进行胃和食管测压。结果：G1的平均胃内压力为1,308 mmHg，G2的平均胃内压力为-0,105 mmHg。 G1和G2的平均食管下压力分别为13,143 mmHg和11,65 mmHg，最高食管压力为35,273 mmHg和27,211 mmHg。 24小时pH值测试显示G2中有26.8％的生理性胃食管反流和73.2％的病理性胃食管反流。两组平均胃内压之间存在统计学上的显着差异（p结论：这项研究表明，食管裂孔疝可显着降低胃内压

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