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首页> 外文期刊>Journal of Clinical Sciences >Pattern of presentation, treatment, and determinants of outcome of pediatric oncology cases at a tertiary institution in Lagos
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Pattern of presentation, treatment, and determinants of outcome of pediatric oncology cases at a tertiary institution in Lagos

机译：拉各斯一家大专院校小儿肿瘤科病例的表现，治疗方法和结果决定因素

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Background: Cancers in children are increasing all over the globe, however, the outcome in LMICs is still quite poor due to a myriad of factors. Aim: This review focused on pattern of admissions in a pediatric oncology unit in Lagos, Nigeria and the determinants of outcome. Settings and Design: This was a retrospective descriptive study at the Lagos University Teaching Hospital from January 2015 to July 2017. Common treatment protocols like UKALL, NWTSG etc are adapted for use in the unit. Data Analysis: This was done using SPSS version 22. Results: A total of 178 children were seen at the oncology unit with a slight male preponderance of 1.4:1. The most common malignancy seen was acute lymphoblastic leukemia (20.8%) while retinoblastoma was the commonest solid tumor (19.6%). Mortality rate observed in the period under review was 45% and a large number of patients (22%) abandoned treatment. Conclusion: The management of childhood cancers is still a big challenge in resource constrained settings and a robust health insurance policy will improve outcomes.
机译：背景：全球儿童癌症的发病率正在上升，但是由于多种因素，中低收入国家的结局仍然很差。目的：本综述着重于尼日利亚拉各斯的儿科肿瘤科的入院方式和结果的决定因素。设置与设计：这是自2015年1月至2017年7月在拉各斯大学教学医院进行的一项回顾性描述性研究。该病房采用了UKALL，NWTSG等常见治疗方案。数据分析：这是使用SPSS 22版完成的。结果：在肿瘤科总共看到178名儿童，男性占1.4：1的比例略有优势。看到的最常见的恶性肿瘤是急性淋巴细胞白血病（20.8％），而视网膜母细胞瘤是最常见的实体瘤（19.6％）。在本报告所述期间观察到的死亡率为45％，大量患者（22％）放弃了治疗。结论：在资源有限的环境中，儿童期癌症的管理仍然是一个巨大的挑战，而强有力的健康保险政策将改善结果。

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