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Metastatic oral and maxillofacial tumors in a tertiary referral hospital: Retrospective analysis of eight cases and review of the literature

机译:三级转诊医院的口腔和颌面部转移性肿瘤:八例回顾性分析并文献复习

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Introduction: Metastatic tumors are lesions that originate from a distant site and manifest in their secondary site remote from the primary. They are said to be rare in the maxillofacial region. Patients and Methods: This was a retrospective study from the Department of Dental and Maxillofacial Surgery and Department of Histopathology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, northwest Nigeria, from 2010 to 2016. Results: A total of 259 cases of malignant tumors were seen, of which 8 cases (3.1%) were metastasis. There were four males and four females (ratio 1:1). The age ranged from 20 to 75 years with mean ± standard deviation (55.6 ± 18.8 years). Mandible was the chosen location for all the metastatic tumors in this series with the right body-ramus region frequently involved in 4 (50%), closely followed by the left body-ramus in 3 (37.5%) and 1 (12.5%) case seen in the parasymphyseal-symphyseal region. The prostate was the most frequent primary organ that metastasized to the maxillofacial region (3, 37.5%). Conclusion: High level of suspicion is required for early identification of these lesions, and prompt referral is paramount as these tumors can be the first evidence of hidden malignancy at distant sites such as prostate, colon, lungs, breast, and kidneys.
机译:简介:转移性肿瘤是起源于远处的病变,并在远离原发灶的继发部位出现。据说它们在颌面部位很少见。患者与方法:这是一项自2010年至2016年来自尼日利亚西北部索科托市Usmanu Danfodiyo大学教学医院牙科与颌面外科和组织病理学系的回顾性研究。结果:共观察到259例恶性肿瘤,其中8例(3.1%)为转移。有四男一女(比率1:1)。年龄范围为20到75岁,平均±标准差(55.6±18.8岁)。下颌骨是该系列中所有转移性肿瘤的选择位置,右体-ram骨区域经常涉及4(50%),紧随其后的是3(37.5%)和1(12.5%)病例的左体-region骨区域见于副鞘-共生区。前列腺是转移到颌面部的最常见的主要器官(3,37.5%)。结论:需要高度怀疑,以及早发现这些病变,而及时转诊至为重要,因为这些肿瘤可能是前列腺,结肠,肺,乳腺和肾脏等遥远部位隐匿性恶性肿瘤的首个证据。

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