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首页> 外文期刊>Journal of Clinical Sciences >Aortic aneurysm: A life-threatening condition in a low-resource nation
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Aortic aneurysm: A life-threatening condition in a low-resource nation

机译：主动脉瘤：资源匮乏国家的威胁生命的疾病

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Background: Aortic aneurysm is said to be uncommon in the black population; however, with the modification in lifestyle of the dark-skinned people, and improved diagnostic facilities in Sub-Saharan African nations, a surge in its presentation is more likely. If undiagnosed, aortic aneurysm can be catastrophic. We determined the epidemiology pattern and outcome of aortic aneurysm at our institution. Materials and Methods: This is a retrospective analysis of patients who presented with aortic aneurysm from 2000 to 2017. A pro forma was designed to analyze the bio data, characteristics of the aneurysms, clinical manifestation, treatment, and outcome. The Crawford, Stanford, and DeBakey criteria were used to classify the aortic aneurysm. The surgical management of the aneurysm was resection and its replacement with synthetic polytetrafluoroethylene prosthesis with antibiotic prophylaxis under general anesthesia. Results: A total of 17 patients were recruited, with a mean age of 62.75 ± 20.92 years. A high proportion were above 65 years, i.e., 7 (41.2%), and male gender, i.e., 10 (58.8%). The most common location of aortic aneurysm using Crawford criteria was Type IV followed by Type I, with Stanford criteria being Stanford Type B (13) and with DeBakey being Type III (3). Five operated were fusiform in shape. A higher proportion of patients, i.e., 14 (82.4%), had coexisting hypertension, and a positive history of smoking, i.e., 7 (41.2%). The 30-day mortality was 64.7%, the operative mortality was 35.3%, and three patients (17.6%) were loss to follow-up. A positive history of smoking increased the risk of dead, relative risk 3.375, 95% confidence interval 0.677–5.909, P = 0.04. Conclusion: Aortic aneurysm, though uncommon, is not a rare disease among cardiovascular disorders in a low-resource environment. The most common shape and location were fusiform and Stanford Type B or DeBakey Type III, respectively. There was associated high 30-day mortality (64.7%).
机译：背景：在黑人人群中，主动脉瘤据说不常见。然而，随着黑皮肤人生活方式的改变以及撒哈拉以南非洲国家诊断设备的改进，其出现的可能性更大。如果不确诊，主动脉瘤可能是灾难性的。我们确定了我们机构的主动脉瘤的流行病学模式和结果。材料和方法：这是对2000年至2017年主动脉瘤患者的回顾性分析。设计了备考表，以分析生物数据，动脉瘤的特征，临床表现，治疗和结果。使用Crawford，Stanford和DeBakey准则对主动脉瘤进行分类。动脉瘤的手术处理是切除，并在全身麻醉下用合成的聚四氟乙烯假体代替，并用抗生素预防。结果：总共招募了17名患者，平均年龄为62.75±20.92岁。 65岁以上的比例很高，即7岁（41.2％），而男性则是10岁（58.8％）。使用克劳福德标准最常见的主动脉瘤位置是IV型，其次是I型，斯坦福标准是B型斯坦福（13），而DeBakey是III型（3）。五例手术呈梭形。较高比例的患者，即14位（82.4％）患有高血压并存吸烟史，即7位（41.2％）。 30天死亡率为64.7％，手术死亡率为35.3％，三名患者（17.6％）失访。吸烟的积极史增加了死亡风险，相对风险为3.375，95％的置信区间为0.677-5.909，P = 0.04。结论：在资源匮乏的环境中，主动脉瘤虽然不常见，但在心血管疾病中并不是罕见的疾病。最常见的形状和位置分别是梭形和斯坦福B型或DeBakey III型。与之相关的30天高死亡率（64.7％）。

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