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Submitral left ventricular aneurysm: Characteristics, diagnosis, management, and outcome

机译:左室主动脉瘤:特征,诊断,治疗和结果

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Left ventricular (LV) aneurysm (LVA) is an uncommon cardiac disorder. There is no documented report from Ethiopia. Our objective was to discuss a case of LVA we encountered and analyze the clinical characteristics, diagnosis, management modalities, and outcome of patients with LVA from published studies over the last 200 years. in addition to the case we encountered, we searched PubMed for publications on patients with LVA and analyzed those reported since 1816. We identified 369 patients with LVA. The mean age at diagnosis was 31.7 ± 21.7 years, and 52.3% of them were males. It was more frequently reported from Africa (32.0%) and Europe (31.4%). The inferior part of the left ventricle including the submitral area is the most frequently (51.8%) reported location for LVA. Diagnosis was made coincidentally in most (40.1%) of the patients. The presenting features in those symptomatic patients were dyspnea or heart failure (HF) (23.8%), rhythm disturbances (18.2%), chest pain (10.6%), syncope (8.4%), thrombus (10.8%), or embolic events (5.4%). The universally used diagnostic modality was echocardiography. Electrocardiography (61%), chest X-ray (31.2%), cardiac catheterization (42.8%), computed tomography (1.3%), and magnetic resonance imaging (1.6%) were used as confirmatory or complementary imaging tests. During the follow-up period, death from cardiac causes occurred in 13.1% of the patients, with the leading cause of the cardiac death being congestive HF (51.9%). LVA has varied clinical features with potentially deleterious outcomes. While close follow-up with echocardiography in such patients is necessary, building the local expertise in surgical management of such patients is recommended as it has implications on individual patient, proper health-care utilization, and health-care costs.
机译:左室(LV)动脉瘤(LVA)是一种罕见的心脏疾病。埃塞俄比亚没有书面报告。我们的目的是讨论一个我们遇到的LVA病例,并分析最近200年来发表的研究对LVA患者的临床特征,诊断,治疗方式和结果的影响。除了我们遇到的案例外,我们还在PubMed中搜索了有关LVA患者的出版物,并分析了1816年以来的报道。我们确定了369例LVA患者。诊断时的平均年龄为31.7±21.7岁,其中52.3%是男性。非洲(32.0%)和欧洲(31.4%)的报道较多。左心室下半部(包括屈服区)是LVA最常报告的位置(51.8%)。绝大多数(40.1%)患者同时进行了诊断。这些有症状患者的表现为呼吸困难或心力衰竭(HF)(23.8%),节律紊乱(18.2%),胸痛(10.6%),晕厥(8.4%),血栓(10.8%)或栓塞事件( 5.4%)。普遍使用的诊断方式是超声心动图。心电图检查(61%),胸部X线检查(31.2%),心脏导管检查(42.8%),计算机断层扫描(1.3%)和磁共振成像(1.6%)被用作确认性或补充性成像检查。在随访期间,因心脏原因死亡的患者占13.1%,其中因心脏充血性心力衰竭而死亡的主要原因(51.9%)。 LVA具有变化的临床特征,具有潜在的有害后果。尽管有必要对此类患者进行超声心动图的密切随访,但建议在此类患者的手术管理方面建立当地的专业知识,因为这会影响单个患者,适当的医疗保健利用和医疗保健成本。

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