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Role of scrape cytology in ovarian neoplasms

机译:刮刮细胞学在卵巢肿瘤中的作用

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Aim:The present study was done to evaluate the role of scrape cytology in the diagnosis of ovarian neoplasm and its utilization for teaching pathology residents.Materials and Methods:This was a prospective study on 50 solid/solid-cystic ovarian neoplasms sent in 10% buffered formalin. Scrapings obtained from the fresh cut surface of tumors were smeared uniformly on to glass slides, immediately fixed in 95% ethyl alcohol and stained with hematoxylin and eosin stain.Results:The overall diagnostic accuracy of scrape cytology has been satisfactory with 92% of cases correlating with the final diagnosis. Characteristic cytological pattern was noted in various types of surface epithelial, sex cord stromal and germ cell tumors. The technique had limited value in mucinous tumors to distinguish borderline cases from invasive carcinoma. Two mucinous carcinomas were diagnosed as borderline mucinous tumor and two endometrioid carcinomas were misinterpreted as cystadenocarcinoma on scrape cytology. Formalin did not interfere or produce any remarkable changes in cytomorphology.Conclusions:Scrape cytology is a simple, rapid, accurate, inexpensive adjunctive cytodiagnostic technique and its routine utilization in ovarian lesions could aid in expanding the cytological knowledge of ovarian neoplasms.
机译:目的:本研究旨在评估刮擦细胞学在卵巢肿瘤诊断中的作用及其在病理学住院医师教学中的应用。材料与方法:这是一项前瞻性研究,以50%的固体/固体囊性卵巢肿瘤为研究对象。缓冲福尔马林。将新鲜切开的肿瘤表面的碎片均匀涂在载玻片上,立即用95%乙醇固定,并用苏木精和曙红染色。结果:刮取细胞学的总体诊断准确性令人满意,有92%的病例最终诊断。在各种类型的表面上皮,性索基质和生殖细胞肿瘤中注意到了特征性细胞学模式。该技术在粘液性肿瘤中区分边缘性病例和浸润性癌的价值有限。在刮擦细胞学上,两个粘液癌被诊断为交界性粘液瘤,两个子宫内膜样癌被误解为囊腺癌。结论:刮壁细胞学是一种简单,快速,准确,廉价的辅助细胞诊断技术,其在卵巢病变中的常规应用可有助于扩大卵巢肿瘤的细胞学知识。

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