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首页> 外文期刊>Journal of dermatology and cosmetic. >Comparison of the efficacy of betamethasone lotion with clotrizone (betamethasone + clotrimazole) lotion in seborrheic dermatitis of face and scalp
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Comparison of the efficacy of betamethasone lotion with clotrizone (betamethasone + clotrimazole) lotion in seborrheic dermatitis of face and scalp

机译：倍他米松乳液和克霉唑酮（倍他米松+克霉唑）乳液在面部和头皮脂溢性皮炎中的疗效比较

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Background and Aim: Seborrhoic dermatitis is one of the most common diseases in dermatology with a prevalence of about 2%. Many treatments have been used for this disease. This Study aimed to investigate the efficacy of betamethasone lotion compared with clotrizone lotion in patients with seborrheic dermatitis of face and scalp. Methods: This double blind study was performed on 60 patients with seborrheic dermatitis older than 18 years, who refered to Emam Reza hospital, Mashhad. Patients were divided into two groups: clotrizone (31) and betamethasone group (29 patients). Patients were treated for a month. We evaluated severity of pruritus, erythema and desquamation of the face and scalp. Results: The average age of patients participating in the study was 33.1 years (18 to 56 years) and 56.7% of patients were male. No significant differences were found in age and gender between the two groups (P 0.05). Both treatments reduced severity of erythema and desquamation of the face and scalp (P0.001). Two weeks after treatment, clotrizone had better performance, but there after both lotions had similar effect. Betamethasone reduced pruritus more than clotrizone. Conclusion: This study showed that both betamethasone and clotrizone were effective. Clotrizone has better impact on the severity of erythema and scaling and betamethasone has better effect on improving the severity of pruritus.
机译：背景与目的：脂溢性皮炎是皮肤病学中最常见的疾病之一，患病率约为2％。已经对该疾病使用了许多治疗方法。这项研究旨在研究倍他米松乳液与克霉唑酮乳液在面部和头皮脂溢性皮炎患者中的疗效。方法：这项双盲研究是对60名18岁以上的脂溢性皮炎患者进行的，这些患者转诊至马什哈德的Emam Reza医院。患者分为两组：克霉唑酮（31）和倍他米松组（29例）。患者接受了一个月的治疗。我们评估了瘙痒，红斑以及面部和头皮脱屑的严重程度。结果：参加该研究的患者的平均年龄为33.1岁（18至56岁），男性患者为56.7％。两组的年龄和性别差异均无统计学意义（P> 0.05）。两种治疗均降低了红斑的严重程度以及面部和头皮的脱皮（P <0.001）。治疗后两周，克霉唑的效果更好，但两种乳液在那之后的效果相似。倍他米松比克霉唑酮更能减少瘙痒。结论：这项研究表明倍他米松和克霉唑酮均有效。克霉唑酮对红斑和脱屑的严重程度有更好的影响，倍他米松对改善瘙痒的严重程度有更好的作用。

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