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首页> 外文期刊>Journal of Applied Oral Science >Tissue reaction to Endométhasone sealer in root canal fillings short of or beyond the apical foramen
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Tissue reaction to Endométhasone sealer in root canal fillings short of or beyond the apical foramen

机译:根尖孔不满或超出根尖孔的根管充填物中对组织内塞米松封闭剂的组织反应

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摘要

OBJECTIVE: This study evaluated the response of periapical tissues to the endodontic sealer Endométhasone in root canal fillings short of or beyond the apical foramen. MATERIAL AND METHODS: Twenty root canals of premolars and incisors of 2 mongrel dogs were used. After coronal access and pulp extirpation, the canals were instrumented up to a size 55 K-file and the apical cemental barrier was penetrated with a size 15 K-file to obtain a main apical foramen, which was widened to a size 25 K-file. The canals were irrigated with saline at each change of file. The root canals were obturated either short of or beyond the apical foramen by the lateral condensation of gutta-percha and Endométhasone, originating 2 experimental groups: G1: Endométhasone/short of the apical foramen; G2: Endométhasone/beyond the apical foramen. The animals were killed by anesthetic overdose 90 days after endodontic treatment. The individual roots were obtained and serial histological sections were prepared for histomorphological analysis (H&E and Brown & Brenn techniques) under light microscopy. The following parameters were examined: closure of the apical foramen of the main root canal and apical opening of accessory canals, apical cementum resorption, intensity of the inflammatory infiltrate, presence of giant cells and thickness and organization of the apical periodontal ligament. Each parameter was scored 1 to 4, 1 being the best result and 4 the worst. Data were analyzed statistically by the Wilcoxon nonparametric tests (p=0.05). RESULTS: Comparing the 2 groups, the best result (p<0.05) was obtained with root canal filling with Endométhasone short of the apical foramen but a chronic inflammatory infiltrate was present in all specimens. CONCLUSIONS: Limiting the filling material to the root canal space apically is important to determine the best treatment outcome when Endométhasone is used as sealer.
机译:目的:本研究评估了根尖部充盈(不包括根尖孔)或根尖孔以外的根尖组织对根尖封闭剂Endométhasone的反应。材料与方法:使用20只杂种犬的前磨牙和门齿的20根根管。在冠状动脉入路和牙髓摘除后,将根管植入器械直至达到55 K锉刀的大小,并以15 K锉刀穿透根尖的牙骨屏障,以获得一个主要的根尖孔,将其扩大至25 K锉刀的大小。每次更换锉刀时,用盐水冲洗运河。牙胶-牙甲和内多米松的侧向凝结将根管阻塞在根尖孔的外侧或上方,这是由两个实验组组成的。 G2:Endométhasone/超出根尖孔。牙髓治疗后90天通过麻醉药过量杀死动物。获得了单个根,并准备了连续的组织学切片以在光学显微镜下进行组织形态学分析(H&E和Brown&Brenn技术)。检查了以下参数:主根管的根尖孔的闭合和附属根管的根尖的开口,根尖牙骨质的吸收,炎性浸润的强度,巨大细胞的存在以及根尖牙周膜的厚度和组织。每个参数的评分为1-4,其中1为最佳结果,4为最差。通过Wilcoxon非参数检验对数据进行统计学分析(p = 0.05)。结果:两组比较,根管内未加根尖孔的内苯二甲砜充填根管效果最好(p <0.05),但所有标本中均存在慢性炎症浸润。结论:将Endométhasone用作封闭剂时,将填充材料限制在根管间隙对于确定最佳治疗效果非常重要。

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