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首页> 外文期刊>Journal of Applied Medical Sciences >Pattern and Distribution of HIV associated Pulmonary Tuberculosis Lesion on Chest Radiograph in Nigeria
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Pattern and Distribution of HIV associated Pulmonary Tuberculosis Lesion on Chest Radiograph in Nigeria

机译：尼日利亚胸部X线片上HIV相关性肺结核病变的类型和分布

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We compared the pattern and distribution of pulmonary lesion on chest radiograph of HIV patients with CD4 count < or ≥200cells/μl and HIV-1RNA viral load < or ≥log105. Of the 133 patients consecutively recruited, 84 (63.2%) had CD4 count <200 cells/μ. Patients with CD4 count <200 cells/μ had consolidation (15.5% vs 28. P = 0.054) and streaky changes 39.3% vs 55.9%, P = 0.049) less often. Pulmonary lesions involving upper and middle radiological zones were less common in cohort with CD4 count < 200cells/μ (11.9% vs 30.5%, P = 0.006), conversely middle and lower zone involvement were most often seen in them (27.4% vs 15.3%, P = 0.008). Patients with HIV-1 RNA viral load ≥05copies/ml had nodular lesions less often (31.7% vs 55.1%, p = 0.038) and more often had hilar or mediastinal lymphadenopathy (22.0% vs 7.3%, P = 0.012). Lower zone involvement was predominantly seen in cohort with HIV-1 RNA viral load ≥05copies/ml (19.5% vs 0.01%, p = 0.000). Our study demonstrates association between HIV disease stage with pattern and distribution of certain tuberculosis lesion on chest radiograph. Knowledge of immunological and virological parameters is important to clinicians and radiologist when evaluating CXR findings in HIV-infected patients.
机译：我们在CD4计数≤200细胞/μl和HIV-1RNA病毒载量≤log105的HIV患者的胸部X光片上比较了肺部病变的类型和分布。在连续招募的133例患者中，有84例（63.2％）的CD4计数<200细胞/μ。 CD4计数＜200个细胞/μm的患者较少出现巩固（15.5％vs 28. P = 0.054）和条纹变化39.3％vs 55.9％，P = 0.049）。在CD4计数<200个细胞/μ的队列中，涉及上，中放射区的肺部病变较少见（11.9％vs 30.5％，P = 0.006），相反，中，下区受累最常见（27.4％vs 15.3％） ，P = 0.008）。 HIV-1 RNA病毒载量≥05拷贝/ ml的患者结节性病变的发生率较低（31.7％对55.1％，p = 0.038），而肺门或纵隔淋巴结病的发生率较高（22.0％vs 7.3％，P = 0.012）。在HIV-1 RNA病毒载量≥05拷贝/ ml的队列中主要观察到较低区域的受累（19.5％vs 0.01％，p = 0.000）。我们的研究表明，在胸部X光片上，HIV疾病分期与某些肺结核病灶的分布方式和分布之间存在关联。在评估HIV感染患者的CXR结果时，对免疫学和病毒学参数的了解对临床医生和放射线医师很重要。

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