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首页> 外文期刊>Journal of Applied Medical Sciences >Histopathological Determination of Placental Malaria and its Relation to Fetal Birth Weight
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Histopathological Determination of Placental Malaria and its Relation to Fetal Birth Weight

机译：胎盘疟疾的组织病理学测定及其与胎儿出生体重的关系

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Background: Placental malaria(PM) is a serious public health concern especially in endemic areas among primigravidae. This form of malaria does not just affect the woman but the foetus. It has been identified as the leading cause of complications and high morbidity during delivery in the tropics. Methods: This is a cross-sectional study involving 181 randomly selected pregnant women at the point of delivery. Placental samples were collected from a healthy pericentic area, fixed in 10% neutral buffered formal saline, processed into paraffin wax and 5μm thin sections stained by Haematoxylin & Eosin(H&E) and Giemsa's method and then viewed microscopically. A standard questionnaire was also administered at the point of delivery and analysed. Other information collected at point of delivery include vital status at birth, birth weight, sex, malformation(if any) and placental weight. Results: Placental malaria was recorded in 30(16.6%) of the subjects, while only 13.3% of those with PM had babies with low birthweight. 97.8% of the women were on prophylactic drugs and about the same percentage attend Antenatal care(ANC). Conclusion: Our study shows that if pregnant women attend ANC and are placed on prophylactic drugs, placental malaria may not lead to low birthweight and other complications associated with the infection.
机译：背景：胎盘疟疾是一个严重的公共卫生问题，尤其是在初产妇流行地区。这种形式的疟疾不仅影响女性，而且影响胎儿。它已被确定为热带地区分娩过程中并发症和高发病率的主要原因。方法：这是一项横断面研究，涉及分娩时随机选择的181名孕妇。从健康的腹膜周围区域收集胎盘样品，将其固定在10％中性缓冲生理盐水中，处理成石蜡，并用苏木精和曙红（H＆E）和Giemsa法染色5μm薄片，然后在显微镜下观察。在交付时还进行了标准问卷调查并进行了分析。分娩时收集的其他信息包括出生时的生命状况，出生体重，性别，畸形（如果有）和胎盘重量。结果：30例受试者中有胎盘疟疾（16.6％），而PM仅有13.3％的婴儿体重低。 97.8％的妇女使用了预防性药物，而接受产前保健（ANC）的妇女所占的比例相同。结论：我们的研究表明，如果孕妇参加ANC并使用预防药物，则胎盘疟疾可能不会导致低出生体重和其他与感染相关的并发症。

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