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首页> 外文期刊>Journal of Contemporary Brachytherapy >ENT COBRA ONTOLOGY: the covariates classification system proposed by the Head & Neck and Skin GEC-ESTRO Working Group for interdisciplinary standardized data collection in head and neck patient cohorts treated with interventional radiotherapy (brachythera
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ENT COBRA ONTOLOGY: the covariates classification system proposed by the Head & Neck and Skin GEC-ESTRO Working Group for interdisciplinary standardized data collection in head and neck patient cohorts treated with interventional radiotherapy (brachythera

机译：ENT COBRA ONTOLOGY：“头颈与皮肤GEC-ESTRO工作组”提出的协变量分类系统，用于在接受介入放射治疗的头颈患者队列中进行跨学科标准化数据收集

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Purpose Clinical data collecting is expensive in terms of time and human resources. Data can be collected in different ways; therefore, performing multicentric research based on previously stored data is often difficult. The primary objective of the ENT COBRA (COnsortium for BRachytherapy data Analysis) ontology is to define a?specific terminological system to standardized data collection for head and neck (H&N) cancer patients treated with interventional radiotherapy. Material and methods ENT-COBRA is a?consortium for standardized data collection for H&N patients treated with interventional radiotherapy. It is linked to H&N and Skin GEC-ESTRO Working Group and includes 11 centers from 6 countries. Its ontology was firstly defined by a?multicentric working group, then evaluated by the consortium followed by a?multi-professional technical commission involving a?mathematician, an engineer, a?physician with experience in data storage, a?programmer, and a?software expert. Results Two hundred and forty variables were defined on 13 input forms. There are 3 levels, each offering a?specific type of analysis: 1. Registry level (epidemiology analysis); 2. Procedures level (standard oncology analysis); 3. Research level (radiomics analysis). The ontology was approved by the consortium and technical commission; an ad-hoc software architecture (“broker”) remaps the data present in already existing storage systems of the various centers according to the shared terminology system. The first data sharing was successfully performed using COBRA software and the ENT COBRA Ontology, automatically collecting data directly from 3 different hospital databases (Lübeck, Navarra, and Rome) in November 2017. Conclusions The COBRA Ontology is a?good response to the multi-dimensional criticalities of data collection, retrieval, and usability. It allows to create a?software for large multicentric databases with implementation of specific remapping functions wherever necessary. This approach is well-received by all involved parties, primarily because it does not change a?single center’s storing technologies, procedures, and habits.
机译：目的就时间和人力资源而言，临床数据收集非常昂贵。数据可以通过不同的方式收集;因此，基于先前存储的数据进行多中心研究通常很困难。 ENT COBRA（布拉奇疗法数据分析联合会）本体的主要目标是定义一个特定的术语系统，以标准化头颈（H＆N）癌症患者接受介入放疗的标准化数据收集。物质和方法ENT-COBRA是一个为接受介入放射治疗的H＆N患者标准化数据收集的联盟。它与H＆N和Skin GEC-ESTRO工作组联系在一起，包括来自6个国家的11个中心。它的本体首先由一个多中心工作组定义，然后由财团进行评估，然后由一个由多个专业人士组成的技术委员会进行评估，其中包括数学家，工程师，具有数据存储经验的物理学家，程序员和程序员。软件专家。结果在13种输入形式上定义了440个变量。共有3个级别，每个级别提供一种特定的分析类型：1.注册表级别（流行病学分析）; 2.程序级别（标准肿瘤学分析）; 3.研究水平（放射性组学分析）。本体由财团和技术委员会批准;临时软件体系结构（“代理”）根据共享术语系统重新映射各个中心已存在的存储系统中存在的数据。首次数据共享使用COBRA软件和ENT COBRA Ontology成功执行，并于2017年11月直接从3个不同的医院数据库（吕贝克，纳瓦拉和罗马）直接自动收集了数据。结论COBRA Ontology是对多种医学方法的良好回应。数据收集，检索和可用性的维度重要性。它允许为大型多中心数据库创建软件，并在必要时实施特定的重新映射功能。这种方法在所有参与方中都广受好评，主要是因为它不会改变单个中心的存储技术，过程和习惯。

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