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首页> 外文期刊>Journal of Contemporary Brachytherapy >Carotid dosimetry after re-irradiation with 131Cs permanent implant brachytherapy in recurrent, resected head and neck cancer
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Carotid dosimetry after re-irradiation with 131Cs permanent implant brachytherapy in recurrent, resected head and neck cancer

机译：131Cs永久性植入物近距离放疗重新照射后复发，切除的头颈癌患者的颈动脉剂量

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Purpose Permanent seed implant cesium-131 (131Cs) brachytherapy provides highly localized radiation for patients with recurrent head and neck cancer (HNC), who may be ineligible for external beam radiation therapy due to a?high-risk of toxicity. As carotid blowout is a?concern in the setting of re-irradiation, a dose to the carotid artery was examined for 131Cs brachytherapy implants. Material and methods Eleven patients were implanted with 131Cs adjacent to carotid at the time of resection for recurrent HNC. Vascularized tissue flaps were used in some patients. The carotid artery was contoured on the post-implant brachytherapy treatment plan, and the maximum carotid point dose and minimum carotid-seed distances are reported. The incidence of carotid blowout in the follow-up period was also measured. Results The maximum carotid dose was 77 ±52 Gy (range, 3-158 Gy). The closest seed to the carotid artery was 0.8 ±0.8 cm (range, 0.2-2.6 cm). One patient without a?flap experienced carotid blowout, which was attributed to a?non-healing wound rather than to high radiation doses. Conclusions Carotid artery doses from 131Cs are reported. Vascularized tissue flaps should be considered when planning 131Cs brachytherapy.
机译：目的永久性植入物铯131（131Cs）近距离放射疗法可为患有复发性头颈癌（HNC）的患者提供高度局部的放射治疗，这些患者由于毒性高风险而可能不适合进行外部束放射治疗。由于颈动脉井喷与重新照射有关，因此对131 Cs近距离放射治疗植入物检查了颈动脉的剂量。材料和方法11例患者在复发性HNC切除时被植入邻近颈动脉的131Cs。在某些患者中使用了血管化的皮瓣。在植入后近距离放射治疗计划中勾勒出颈动脉轮廓，并报告最大颈动脉点剂量和最小颈动脉种子距离。还测量了随访期间颈动脉爆裂的发生率。结果最大颈动脉剂量为77±52 Gy（范围3-158 Gy）。最接近颈动脉的种子是0.8±0.8 cm（范围0.2-2.6 cm）。一名没有皮瓣的患者经历了颈动脉爆裂，这归因于伤口未愈合，而不是高剂量的辐射。结论已有报道131Cs的颈动脉剂量。计划131Cs近距离治疗时应考虑血管化的皮瓣。

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