Pure primary ovarian choriocarcinoma is an extremely rare and aggressive tumor. It can be of gestational or nongestational in origin. The gestational type can arise from an ovarian pregnancy or can be of metastatic origin from uterine choriocarcinoma. The nongestational type is a very rare germ cell neoplasm. It is important to distinguish between two types of choriocarcinomas as nongestational origin is highly malignant and has worse prognosis than gestational type. But it is very difficult to differentiate by routine histological examination. Nongestational choriocarcinoma has been found to be resistant to single agent chemotherapy. It occurs usually around 13 years of age and is mainly confined to females under 20. Here we report a case of primary pure nongestational choriocarcinoma of the ovary in an unmarried girl of 14 years, diagnosed in 2001 and treated successfully with surgery and combination chemotherapy and remained disease-free till last reporting in September 2013. DOI: http://dx.doi.org/10.3329/jemc.v4i1.18070 J Enam Med Col 2014; 4(1): 56-59
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机译：单纯性原发性卵巢绒毛膜癌是一种极为罕见的侵袭性肿瘤。它的起源可以是妊娠的或非妊娠的。妊娠类型可以是卵巢妊娠引起的，也可以是子宫绒毛膜癌的转移性起源。非妊娠型是非常罕见的生殖细胞肿瘤。重要的是要区分两种绒毛膜上皮癌，因为非妊娠起源的恶性程度高，预后比妊娠类型差。但是通过常规组织学检查很难区分。已发现非妊娠绒毛膜癌对单药化疗耐药。它通常发生在13岁左右，并且主要局限于20岁以下的女性。在这里，我们报道了一例未婚的14岁女孩的原发性单纯性卵巢非绒毛膜绒毛膜上皮癌，该病例于2001年诊断出，并通过手术，联合化学疗法和直到2013年9月的最后报告为止，该病一直没有病。DOI：http：//dx.doi.org/10.3329/jemc.v4i1.18070 J Enam Med Col 2014; 4（1）：56-59
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