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首页> 外文期刊>Dementia & Neuropsychologia >Subjective memory complaints associated with depression and cognitive impairment in the elderly: A systematic review
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Subjective memory complaints associated with depression and cognitive impairment in the elderly: A systematic review

机译：与老年人抑郁和认知障碍相关的主观记忆投诉：系统评价

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The aging process can be accompanied by a slight decline in cognitive functioning, and subjective memory complaints (SMC) appear to be common in the elderly population. OBJECTIVE: To determine whether SMC is associated with cognitive loss or depression and can predict dementia. METHODS: A systematic review of the literature was conducted. Articles were selected on the following databases, LILACS, SCOPUS, SCiELO, PubMed and Web of Science from August to October 2013. Article selection was based on inclusion and exclusion criteria. Studies published between 2010 and 2013, written in English, Spanish or Portuguese, involving populations 65 years or older, were included. Reviews were excluded. RESULTS: After the selection, a summary of the 20 articles retrieved was carried out. Of the total articles retrieved, fifteen were cross-sectional studies and five were longitudinal studies. Most of the cross-sectional studies associated SMC with depression, objective cognitive impairment and anxiety. The emergence of dementia in people with SMC was evidenced in longitudinal studies. Albeit less frequently, SMC were also associated with reduced quality of life, impairment in Activities of Daily Living (ADL), emergence of neuropsychiatric symptoms, lower hippocampal volume, amygdala volume reduction, increased activation of the left temporal, bilateral thalamus, caudate and posterior cingulate, and with the occurrence of ApoE ε4. CONCLUSION: SMC may be associated with changes in mood and/or cognition, and its occurrence appears to increase the likelihood of dementia. In order to further our understanding of the topic, future studies should consider the recruitment of representative samples with control groups and longitudinal designs.
机译：衰老过程可能伴随着认知功能的轻微下降，而主观记忆抱怨（SMC）在老年人口中似乎很常见。目的：确定SMC是否与认知功能减退或抑郁相关，并可以预测痴呆。方法：对文献进行了系统的回顾。 2013年8月至10月，在以下数据库（LILACS，SCOPUS，SCiELO，PubMed和Web of Science）中选择了文章。文章的选择基于纳入和排除标准。纳入了2010年至2013年之间以英语，西班牙语或葡萄牙语撰写的涉及65岁以上人口的研究。评论被排除在外。结果：选择后，对检索到的20篇文章进行了总结。在检索到的所有文章中，有15篇是横断面研究，有5篇是纵向研究。大多数横断面研究将SMC与抑郁症，客观认知障碍和焦虑症相关联。纵向研究证实了SMC患者痴呆症的出现。 SMC的发生频率虽然较低，但也与生活质量下降，日常生活活动（ADL）障碍，神经精神症状的出现，海马体积降低，杏仁核体积减小，左颞，双侧丘脑，尾状和后部激活增加有关。扣带回，并伴有ApoEε4的出现。结论：SMC可能与情绪和/或认知的改变有关，其发生似乎增加了痴呆的可能性。为了加深我们对该主题的理解，未来的研究应考虑募集具有对照组和纵向设计的代表性样品。

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