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首页> 外文期刊>Dementia and Geriatric Cognitive Disorders Extra >Language in Amnestic Mild Cognitive Impairment and Dementia of Alzheimer’s Type: Quantitatively or Qualitatively Different?
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Language in Amnestic Mild Cognitive Impairment and Dementia of Alzheimer’s Type: Quantitatively or Qualitatively Different?

机译：遗忘性轻度认知障碍和老年痴呆症类型的语言：在数量或质量上有所不同？

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Background/Aims: The purpose of this study was to explore language differences between individuals diagnosed with amnestic mild cognitive impairment multiple domain (aMCIm) and those with probable Alzheimer’s disease, with a goal of (i) characterizing the language profile of aMCIm and (ii) determining whether the profiles of dementia of Alzheimer’s type (DAT) and aMCIm individuals are on a continuum of one diagnostic entity or represent two distinct -cognitive disorders. Methods: Language data from 28 patients with consensus diagnosis of aMCIm and DAT derived from a retrospective chart review were compared to that of healthy controls. Results: A non-parametric statistic established that there was no significant difference between groups in age, years of education or duration of symptoms and that expressive language was found to be relatively intact in both patient groups. In contrast, both groups exhibited significant impairments on receptive language tests and on linguistically complex tasks that rely on episodic memory and executive functions. Individuals with aMCIm and DAT present with configurations of language features that are largely in parallel to each other and reflect predominantly quantitative differences. Conclusion: Language tests provide an important contribution to the diagnostic process in their capacity to identify language impairments at an early stage. Understanding the nature of language decline is critically important to the intervention process as this information would inform cognitive intervention approaches aimed at promoting quality of life in people living with MCI and dementia.
机译：背景/目的：本研究的目的是探讨被诊断为轻度认知障碍多域（aMCIm）的人与可能患有阿尔茨海默氏病的人之间的语言差异，目的是（i）表征aMCIm的语言特征，以及（ii ）确定阿尔茨海默氏病（DAT）和aMCIm个体的痴呆状况是在一个诊断实体的连续性上还是代表两种截然不同的认知障碍。方法：将来自回顾性图表回顾的28例aMCIm和DAT共识诊断患者的语言数据与健康对照者的语言数据进行比较。结果：一项非参数统计表明，年龄，受教育年限或症状持续时间各组之间无显着差异，并且发现两个患者组的表达语言相对完整。相反，两组在接受性语言测试和依赖于情节记忆和执行功能的语言复杂任务上均表现出明显的障碍。患有aMCIm和DAT的个人所呈现的语言特征配置在很大程度上彼此平行，并且主要反映出数量上的差异。结论：语言测试在早期识别语言障碍的能力方面为诊断过程做出了重要贡献。理解语言衰退的本质对于干预过程至关重要，因为该信息将为旨在提高MCI和痴呆症患者生活质量的认知干预方法提供信息。

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