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首页> 外文期刊>Journal of epidemiology / >Risk of Adverse Reproductive Outcomes Associated with Proximity to Municipal Solid Waste Incinerators with High Dioxin Emission Levels in Japan
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Risk of Adverse Reproductive Outcomes Associated with Proximity to Municipal Solid Waste Incinerators with High Dioxin Emission Levels in Japan

机译：与日本高二恶英排放水平的城市固体废物焚化炉邻近造成不利的生殖结果风险

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BACKGROUND: Great public concern about health effects of dioxins emitted from municipal solid waste incinerators has increased in Japan. This paper investigates the association of adverse reproductive outcomes with maternal residential proximity to municipal solid waste incinerators. METHODS: The association of adverse reproductive outcomes with mothers living within 10 km from 63 municipal solid waste incinerators with high dioxin emission levels (above 80 ng international toxic equivalents TEQ/m3) in Japan was examined. The numbers of observed cases were compared with the expected numbers calculated from national rates adjusted regionally. Observed/expected ratios were tested for decline in risk or peak-decline in risk with distance up to 10 km. RESULTS: In the study area within 10 km from the 63 municipal solid waste incinerators in 1997-1998, 225, 215 live births, 3, 387 fetal deaths, and 835 infant deaths were confirmed. None of the reproductive outcomes studied here showed statistically significant excess within 2 km from the incinerators. However, a statistically significant peak-decline in risk with distance from the incinerators up to 10 km was found for infant deaths (p=0.023) and infant deaths with all congenital malformations combined (p=0.047), where a “peak” is detected around 1-2 km. CONCLUSION: Our study shows a peak-decline in risk with distance from the municipal solid waste incinerators for infant of deaths and infant deaths with all congenital malformations combined. However, due to the lack of detailed exposure information to dioxins around the incinerators, the observed trend in risk should be interpreted cautiously and there is a need for further investigation to accumulate good evidence regarding the reproductive health effects of waste incinerator exposure.
机译：背景：在日本，公众日益关注从城市固体废物焚化炉中排放的二恶英对健康的影响。本文研究了不良生殖结果与孕妇居住区靠近城市固体废物焚化炉的关系。方法：研究了日本63座二恶英排放水平高（国际毒性当量TEQ / m 3 超过80 ng的城市固体废物焚化炉）周围10公里以内的母亲与生殖不良结局的关系。将观察到的病例数与根据地区调整后的国家费率计算出的预期数进行比较。测试了观测/期望比率的风险下降或最大距离下降的风险（最大距离为10 km）。结果：在1997年至1998年的研究区域中，距63座城市固体废物焚化炉10公里以内，已确认225例，215例活产，3 387例胎儿死亡和835例婴儿死亡。此处所研究的生殖结果均未显示出距焚化炉2公里以内的统计学显着过量。但是，发现婴儿死亡（p = 0.023）和所有先天性畸形合并死亡（p = 0.047）的婴儿死亡（p = 0.023）和距焚化炉距离达10 km的危险的统计学显着峰值下降。约1-2公里。结论：我们的研究显示死亡婴儿和所有综合性先天畸形婴儿死亡与城市固体废物焚化炉距离的风险下降最大。但是，由于缺乏关于焚化炉周围二恶英的详细接触信息，应谨慎解释观察到的风险趋势，并且有必要进行进一步的研究以积累有关废物焚烧炉对生殖健康影响的良好证据。

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