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Performance on the RI-48 Cued Recall Test Best Predicts Conversion to Dementia at the 5- and 10-Year Follow-Ups

机译:RI-48提示召回测试的性能可以最好地预测在5年和10年的随访中是否会转变为痴呆症。

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Background: TheRI-48 cued recall test was devised to discriminate between healthy elderly and patients with mild cognitive impairment who are at risk of developing Alzheimer’s disease (AD). However, no long-term follow-up studies have been conducted using this test. Methods: We analyzed the predictive power of the RI-48 test for determining the patients who will convert to AD dementia within the decade after testing. During 10 years, we followed up 40 non-demented patients who attended our Memory Clinic and underwent complete neuropsychological evaluation including the RI-48. Results: Of the 40 patients, 21 developed dementia (converters, CO) and 19 remained stable patients (SP). Of the tests performed at inclusion, only the RI-48 (p < 0.0001) and semantic fluency (p = 0.030) tests gave significantly different results between CO and SP. Conclusion: The RI-48 had the best overall diagnostic accuracy at 5- and at 10-year follow-ups.
机译:背景:RI-48提示回忆测试旨在区分健康的老年人和有轻度认知障碍且有患阿尔茨海默氏病(AD)风险的患者。但是,尚未使用该测试进行长期的随访研究。方法:我们分析了RI-48测试对确定测试后十年内将转化为AD痴呆的患者的预测能力。在10年中,我们对40名非痴呆患者进行了随访,这些患者参加了我们的记忆诊所并接受了包括RI-48在内的完整的神经心理学评估。结果:在40例患者中,有21例发展为痴呆(转化器,CO),而19例仍保持稳定(SP)。在包含时执行的测试中,只有RI-48(p <0.0001)和语义流利度(p = 0.030)测试在CO和SP之间给出了显着不同的结果。结论:RI-48在5年和10年的随访中具有最佳的总体诊断准确性。

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