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首页> 外文期刊>Dementia and Geriatric Cognitive Disorders Extra >Positive FP-CIT SPECT (DaTSCAN) in Clinical Alzheimer’s Disease – An Unexpected Finding?
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Positive FP-CIT SPECT (DaTSCAN) in Clinical Alzheimer’s Disease – An Unexpected Finding?

机译：临床阿尔茨海默氏病中FP-CIT SPECT（DaTSCAN）阳性-意外发现？

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Clinically, Alzheimer’s disease (AD) is by far the most common cause of dementia. Criteria for the diagnosis of dementia with Lewy bodies (DLB) are highly specific but not at all sensitive, which is reflected by the higher number of DLB cases detected histopathologically at autopsy. Imaging of dopamine transporter with FP-CIT SPECT is one possibility to increase sensitivity. Pathological confirmation was also included in the revised consensus criteria for the diagnosis of DLB. However, in the absence of parkinsonism, one of the core features, a clinical diagnosis of AD is more likely. The role of FP-CIT SPECT in DLB diagnosis remains to be clarified. Based on our 3 case reports and a review of the literature, the utility of this imaging method in the differential diagnosis of AD and DLB is highlighted.
机译：在临床上，阿尔茨海默氏病（AD）是迄今为止痴呆症最常见的病因。用路易体（DLB）诊断痴呆的标准是高度特异性的，但一点也不敏感，这在尸检中通过组织病理学检测到的DLB病例较多。用FP-CIT SPECT对多巴胺转运蛋白进行成像是增加灵敏度的一种可能性。病理学确认也包括在诊断DLB的修订共识标准中。然而，在缺乏帕金森氏症（核心特征之一）的情况下，AD的临床诊断可能性更高。 FP-CIT SPECT在DLB诊断中的作用仍有待阐明。基于我们的3例病例报告和文献综述，该成像方法在AD和DLB鉴别诊断中的实用性得到了强调。

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